CleanCap Reagent AU
目录号 : GN20150
CleanCap Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1.
Sample solution is provided at 25 µL, 10mM.
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CleanCap Reagent AU is designed for the co-transcriptional capping of mRNA to produce an mRNA with naturally occurring Cap 1. CleanCap Reagent AU was specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV) and Sindbis virus (SIN). The positive sense strand genomes of these viruses start with a 5’-AU... Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy cotranscriptional capping methods anti-reverse cap analog (ARCA). CleanCap can be used in conjunction with GlpBio’s catalog of modified NTPs.
| purity | >95.00% | Extinction Coefficient | 33,400 Lmol-1cm-1 at 258 nm |
| 分子式 | C31H42N12O25P4 (free acid) | 分子量 | 1106.6 g/mole (free acid) |
| Salt Form | Na+ | Concentration | 100 mM |
| Buffer | H2O | 储存条件 | -20°C or below |
| Synonyms | CleanCap AU for Self-Amplifying mRNA, CleanCap Reagent AU for co-transcriptional capping of mRNA, m7G(5')ppp(5')(2'OMeA)pU | Backbone | 5'-5'-Triphosphate |
| Base Analog | Adenosine, Uridine | Sugar Type | RNA |
| Nucleotide Category | Cap analogs | ||
| Applications | CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases | ||
Quality Control & SDS
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