3'Ome-m7GpppAmpG ammonium
(Synonyms: m7GpppAmpG) 目录号 : GC685423'Ome-m7GpppAmpG ammonium 是一种含有锁核酸 (LNA) 分子的三核苷酸帽类似物。3'Ome-m7GpppAmpG ammonium 具有显著的翻译效率。3'Ome-m7GpppAmpG ammonium 可用作 mRNA 疫苗和 mRNA 转染领域的潜在分子生物学工具，如蛋白质生产、基因治疗和抗癌免疫。
Sample solution is provided at 25 µL, 10mM.
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3'Ome-m7GpppAmpG ammonium is a trinucleotide Cap analogue containing a locked nucleic acid (LNA) molecule. 3'Ome-m7GpppAmpG ammonium shows a significant translational efficiency. 3'Ome-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization[1].
[1]. Senthilvelan A, et al. Trinucleotide Cap Analogue Bearing a Locked Nucleic Acid Moiety: Synthesis, mRNA Modification, and Translation for Therapeutic Applications. Org Lett. 2021 Jun 4;23(11):4133-4136.
| purity | >99.50% | Extinction Coefficient | 30,539 Lmol-1cm-1 at 255 nm |
| 分子式 | C32H43N15O24P4 (free acid) | 分子量 | 1145.60 g/mole (free acid) |
| Salt Form | NH3 | Concentration | 100 mM |
| Buffer | 储存条件 | -20°C or below | |
| Synonyms | m7GpppAmpG | Backbone | 5'-5'-Triphosphate |
| Base Analog | Adenosine, Guanosine | Sugar Type | |
| Nucleotide Category | Cap analogs | ||
| Applications | Adenosine, Guanosine | ||