2-hydroxy Oleic Acid-d17
(Synonyms: FA 18:1;O-d17; 2-HOME-d17; 2-hydroxy-cis-9-Octadecenoic Acid-d17; α-hydroxy-cis-9-Octadecenoic Acid-d17; 2-hydroxy-9(Z)-OME-d-d17; 2-Hydroxyoctadecenoic Acid-d17; 2-OHOA-d17) 目录号 : GC927022-droxy Oleic acid-d17 is intended for use as an internal standard for the quantification of 2-droxy oleic acid by GC- or LC-MS.
Cas No.:1346606-40-3
Sample solution is provided at 25 µL, 10mM.
_1-3.$$$39978408@51.jpg');)
_1-9.$$$38538795@65.jpg');)
_1-9.$$$39112701@51.jpg');)
_1-7.$$$37316672@70.jpg');)
_366-372.$$$36198801@70.jpg');)
.$$$38565142@65.jpg');)
_1867-1883.$$$33248023@67.jpg');)
_eads6055.$$$39977546@45.jpg');)
_eadm9805.$$$40080571@45.jpg');)
_eadj3020.$$$39666821@45.jpg');)
_1-20.$$$39757301@28.jpg');)
_1-24.$$$38898113@28.jpg');)
_273-287.$$$36806353@46.jpg');)
_1-16.$$$37156877@44.jpg');)
_1-19.$$$37460805@44.jpg');)
_1291-1307.$$$34518654@46.jpg');)
2-droxy Oleic acid-d17 is intended for use as an internal standard for the quantification of 2-droxy oleic acid by GC- or LC-MS. 2-droxy Oleic acid is a synthetic monounsaturated droxylated fatty acid. It decreases the lamellar-to-hexagonal transition temperature of bovine liver phosphatidylethanolamine (PE) membranes by approximately 12.5°C when included at a 20：1 molar ratio of PE：2-droxy oleic acid. 2-droxy Oleic acid increases levels of protein kinase C α (PKCα) in and decreases proliferation of A549 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner. It reduces tumor growth in an A549 mouse xenograft model when administered at doses of 75 and 200 mg/kg. 2-droxy Oleic acid has been used in the generation of liposomes.
| Cas No. | 1346606-40-3 | SDF | |
| 别名 | FA 18:1;O-d17; 2-HOME-d17; 2-hydroxy-cis-9-Octadecenoic Acid-d17; α-hydroxy-cis-9-Octadecenoic Acid-d17; 2-hydroxy-9(Z)-OME-d-d17; 2-Hydroxyoctadecenoic Acid-d17; 2-OHOA-d17 | ||
| 化学名 | (Z)-2-hydroxyoctadec-9-enoic-11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-d17 acid | ||
| Canonical SMILES | OC(C(O)=O)CCCCCCC=CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C([2H])([2H])[2H])[2H] | ||
| 分子式 | C18H17D17O3 | 分子量 | 315.6 |
| 溶解度 | Chloroform: Soluble | 储存条件 | -20°C |
| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 3.1686 mL | 15.8428 mL | 31.6857 mL |
| 5 mM | 633.7 μL | 3.1686 mL | 6.3371 mL |
| 10 mM | 316.9 μL | 1.5843 mL | 3.1686 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet