11(Z),14(Z),17(Z)-Eicosatrienoic Acid
(Synonyms: 顺式-11,14,17-二十碳三烯酸) 目录号 : GC40781
A rare ω-3 polyunsaturated fatty acid
Cas No.:17046-59-2
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Eicosatrienoic Acid (20:3ω-3) is a rare polyunsaturated fatty acid of the ω-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. However, it is one of the most active essential fatty acids when assayed for the inhibition of fatty acid elongation/desaturation reactions which convert dietary C-18 fatty acids to C-20 eicosanoid precursors.
| Cas No. | 17046-59-2 | SDF | |
| 别名 | 顺式-11,14,17-二十碳三烯酸 | ||
| Canonical SMILES | CC/C=C\C/C=C\C/C=C\CCCCCCCCCC(=O)O | ||
| 分子式 | C20H34O2 | 分子量 | 306.5 |
| 溶解度 | 0.1 M Na2CO3: 1.7 mg/ml,DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: Miscible | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.2626 mL | 16.3132 mL | 32.6264 mL |
| 5 mM | 0.6525 mL | 3.2626 mL | 6.5253 mL |
| 10 mM | 0.3263 mL | 1.6313 mL | 3.2626 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Occurrence of two nonmethylene-interrupted delta 5 polyunsaturated fatty acids in a delta 6-desaturase-defective mutant of the fungus Mortierella alpina 1S-4
Biochim Biophys Acta 1993 Apr 7;1167(2):137-41.PMID:8466940DOI:10.1016/0005-2760(93)90153-z.
Two non-methylene-interrupted fatty acids, 5(Z),11(Z),14(Z)-eicosatrienoic acid (20:3 delta 5) and 5(Z),11(Z),14(Z),17(Z)-eicosatetraenoic acid (20: 4 delta 5), were found in a delta 6-desaturase-defective mutant of Mortierella alpina 1S-4. 20: 4 delta 5 was detected only when growth was at a temperature lower than 24 degrees C or in a culture medium supplemented with either alpha-linolenic acid or 11(Z),14(Z),17(Z)-Eicosatrienoic Acid. 20: 3 delta 5 was found when growth was at 12-28 degrees C. The amount of 20: 3 delta 5 was greatest (27 mg g-1 dry mycelia) when growth was at 20 degrees C, and it accounted for about 7 wt% of the total fatty acids of the mycelia. The optimum temperature for the accumulation of 20:4 delta 5 was 12 degrees C; there was 6.4 mg 20: 4 delta 5/g dry mycelia. Most of these two fatty acids (more than 75 mol%) was in the triacylglycerol fraction.