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NAE (NEDD8-activating enzyme) catalyzes the initial step of the neddylation signaling that regulates CRLs (cullin-ring ubiquitin ligases) activities. Its downstream effect is linked to cancer cell growth and survival.

  1. Cat.No. Product Name Information
  2. GC15086 MLN4924 NAE inhibitor
  3. GC12175 MLN4924 HCl salt

    NAE inhibitor

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