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PERK

PERK (doublestranded RNA-activated protein kinase-like ER kinase) is localized on endoplasmic reticulum membrane. It is associated with insulin processing and unfolded protein response etc.

  1. Cat.No. Product Name Information
  2. GC39156 AMG PERK 44 AMG PERK 44 是一种口服有效的,高选择性的 PERK 抑制剂,IC50 为 6 nM。AMG PERK 44 对 PERK 的选择性分别是 GCN2 (IC50=7300 nM) 和 B-Raf (IC50 >1000 nM) 的 1000 倍和 160 倍。
  3. GC33006 CCT020312 CCT020312能提供有效的、具有真核起始因子2激酶3(EIF2AK3)选择性的增值控制,同时也是RNA样内质网激酶(PERK)的激动剂。
  4. GC17450 GSK2606414 PERK inhibitor,potent and selective
  5. GC11068 GSK2656157 PERK inhibitor
  6. GC10581 ISRIB PERK signaling inhibitor
  7. GC15462 ISRIB (trans-isomer) PERK inhibitor,potent and selective

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