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MPS1 (monopolar spindle 1 kinase) is a crucial part of the spindle assembly checkpoint. It facilitates the formation of C-MAD2 (closed MAD2) conformer and the MCC (mitotic checkpoint complex) assembly, and involved in the tumor growth.

  1. Cat.No. Product Name Information
  2. GC15283 AZ3146 Mps1 inhibitor,potent and selective
  3. GC19058 BAY1217389 BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
  4. GC32846 BOS-172722 BOS-172722是单极纺锤体1(MPS1)检查点的抑制剂,其IC50值为2nM。
  5. GC33213 CCT251455 CCT251455是有效和选择性的有丝分裂激酶单极纺锤体1(MPS1)抑制剂,IC50值为3nM。
  6. GC34073 Empesertib (BAY 1161909) Empesertib(BAY1161909)是一种有效的Mps1抑制剂,IC50值<1nM。
  7. GC10083 MPI-0479605 Mps1 inhibitor,selective and ATP competitive
  8. GC11292 Mps1-IN-1

    Mps1 kinase inhibitor

  9. GC15745 Mps1-IN-2 Mps1 kinase inhibitor
  10. GC36651 Mps1-IN-3 Mps1-IN-3 是一种有效的,选择性的 MPS1 抑制剂,IC50 值为 50 nM。
  11. GC36752 NMS-P715 NMS-P715 是一种选择性的,ATP 竞争性的 MPS1 抑制剂,IC50 值为 182 nM。
  12. GC13727 TC Mps1 12 Mps1 inhibitor

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