TMED10 Human
目录号 : GP24847Transmembrane Emp24-Like Trafficking Protein 10 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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TMED10 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 177 amino acids (32-185) and having a molecular mass of 20.0kDa.
| Purity | Greater than 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Transmembrane Emp24-Like Trafficking Protein 10 (Yeast); Transmembrane Emp24 Domain-Containing Protein 10; 21 KDa Transmembrane Trafficking Protein; P24 Family Protein Delta-1; p24delta1; Transmembrane Protein Tmp21; S31III125; TMP21; Tmp-21-I; p23. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSISFHLPI NSRKCLREEI HKDLLVTGAY EISDQSGGAG GLRSHLKITD SAGHILYSKE DATKGKFAFT TEDYDMFEVC FESKGTGRIP DQLVILDMKH GVEAKNYEEI AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTR | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. | ||
| Formulation | The TMED10 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol. | ||
TMED10, which has a GOLD domain, belongs to the EMP24/GP25L/p24 family. TMED10, a type I membrane protein is restricted to the plasma membrane and golgi cisternae and takes part in vesicular protein transferring. Additionally, TMED10 is a fragment of the heteromeric secretase complex and controls the complex's gamma- secretase activity without influencing its epsilon-secretase activity. Alterations in TMED10 are linked to early-onset familial Alzheimer's disease. TMED10 has a pseudogene on chromosome 8.
Store at 4°C if entire vial will be used within 2-4 weeks.