Home>>Signaling Pathways>> Others>> Others>>Sylvestroside I

Sylvestroside I Sale

(Synonyms: 林生续断苷I) 目录号 : GC60349

Sylvestroside I 是从 Acicarpha tribuloides 中提取的一种环烯醚萜。

Sylvestroside I Chemical Structure

Cas No.:71431-22-6

规格 价格 库存 购买数量
1mg
¥1,260.00
现货
5mg
¥3,060.00
现货

电话:400-920-5774 Email: sales@glpbio.cn

Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

View current batch:

产品描述

Sylvestroside I is an iridoid isolated from Acicarpha tribuloides[1].

[1]. Capasso, A., et al. Phytochemical and pharmacological studies on medicinal herb Acicarpha tribuloides. International Journal of Pharmacognosy, 1996; 34(4), 255-261.

Chemical Properties

Cas No. 71431-22-6 SDF
别名 林生续断苷I
Canonical SMILES OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2[C@@]3([H])[C@@](C[C@H](OC(C4=CO[C@@H](O[C@]5([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)CO)[C@H](C=C)[C@@H]4CCO)=O)[C@@H]3C)([H])C(C(OC)=O)=CO2
分子式 C33H48O19 分子量 748.72
溶解度 储存条件
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 1.3356 mL 6.6781 mL 13.3561 mL
5 mM 0.2671 mL 1.3356 mL 2.6712 mL
10 mM 0.1336 mL 0.6678 mL 1.3356 mL
  • 摩尔浓度计算器

  • 稀释计算器

  • 分子量计算器

质量
=
浓度
x
体积
x
分子量
 
 
 
*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % saline
计算重置

Research Update

Targeted Separation of COX-2 Inhibitor from Pterocephalus hookeri Using Preparative High-Performance Liquid Chromatography Directed by the Affinity Solid-Phase Extraction HPLC System

Molecules 2021 Dec 6;26(23):7395.PMID:34885975DOI:10.3390/molecules26237395.

Pterocephalus hookeri, as a kind of popular traditional Tibetan medicine, is reputed to treat inflammatory related diseases. In the present work, a cyclooxygenase-2 functionalized affinity solid-phase extraction HPLC system was developed and combined with preparative-HPLC for rapidly screening and separating cyclooxygenase-2 ligand from P. hookeri extracts. Firstly, ligands of cyclooxygenase-2 were screened from extracts by affinity solid-phase extraction HPLC system. Then directed by the screening results, the recognized potential active compounds were targeted separated. As a result, the major cyclooxygenase-2 inhibitor of P. hookeri was obtained with a purity of >95%, which was identified as Sylvestroside I. To test the accuracy of this method, the anti-inflammatory activity of Sylvestroside I was inspected in lipopolysaccharide-induced RAW 264.7 cells. The results show that Sylvestroside I significantly suppressed the release of prostaglandin E2 with dose-dependent, which was in good agreement with the screening result of the affinity solid-phase method. This method of integration of screening and targeted separation proved to be very efficient for the recognition and isolation of cyclooxygenase-2 inhibitors from natural products.