sRANKL (158-316) Mouse
目录号 : GP20895可溶性 RANK 配体 (158-316 a.a) 小鼠重组
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | Soluble Receptor Activator of NFkB Ligand; TNFSF11; TRANCE; TNF-related activation-induced cytokine; OPGL; ODF; Osteoclast differentiation factor; Tumor necrosis factor ligand superfamily member 11; Receptor activator of nuclear factor kappa B ligand; RANKL; Osteoprotegerin ligand; CD254 antigen; sRANKL; sOdf. | ||
| Amino Acid Sequence | Lys158-Asp316, with an N-terminal Met, Accession # Q3TWY5. | ||
| Solubility | It is recommended to reconstitute the lyophilized sRANKL in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized sRANKL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution sRANKL should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50, as measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells, is less than 2ng/ml. | ||
| Formulation | sRANKL protein was lyophilized from a 0.2µm filtered solution in NaH2PO4, NaCl and EDTA. | ||
RANKL binds to tnfrsf11b/opg and to tnfrsf11a/rank. Osteoclast differentiation and activation factor. augments the ability of dendritic cells to stimulate naive t-cell proliferation. May be an important regulator of interactions between t-cells and dendritic cells and may play a role in the regulation of the t-cell-dependent immune response. sRANKL may also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
The ED50, as measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells, is less than 2ng/ml.
Lyophilized sRANKL although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution sRANKL should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.