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SPDP (SPDP Crosslinker)

目录号 GC30018

SPDP是硫化氨的短链交联剂,能够通过NHS脂激活形成二硫键。

规格 价格 库存 购买数量
10mg
¥385.00
现货
50mg
¥1,050.00
现货
100mg
¥1,750.00
现货
200mg
¥2,520.00
现货
500mg
¥5,250.00
现货

Customer Review

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Sample solution is provided at 25 µL, 10mM.

质量管理

Quality Control & SDS

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产品描述

SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) were activated using SPDP .

[1]. Lobedanz S et al. A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug effluxpumps. Proc Natl Acad Sci U S A, 2007 Mar 13, 104(11):4612-7. [2]. Karumuthil-Melethil S et al. Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1diabetes. J Immunol 2010 Jun 15, 184(12):6695-708.

Chemical Properties

Cas No. 68181-17-9 SDF
别名 N/A
化学名 N/A
Canonical SMILES O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
分子式 C12H12N2O4S2 分子量 312.36
溶解度 DMSO : 155 mg/mL (496.22 mM) 储存条件 -20°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置
  • 摩尔浓度计算器

  • 稀释计算器

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*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

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