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RSPO1 Mouse

目录号 : GP24449

R-Spondin-1 Mouse Recombinant

RSPO1 Mouse Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
100μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

RSPO1 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 254 amino acids (21-265a.a.) andhaving a molecular mass of 28.2kDa (Molecular size on SDS-PAGE will appear atapproximately 28-40kDa).RSPO1 is expressed with an 9 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 90.0% as determined by SDS-PAGE. Source Sf9, Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms R-spondin-1; Cristin-3; mCristin-3; Roof plate-specificspondin-1; Rspo1; RSPO; R-spondin 1;R-spondin; Rspondin; CRISTIN3.
Amino Acid Sequence ADPSRGIKGKRQRRISAEGS QACAKGCELC SEVNGCLKCS PKLFILLERN DIRQVGVCLP SCPPGYFDAR NPDMNKCIKCKIEHCEACFS HNFCTKCQEG LYLHKGRCYP ACPEGSTAAN STMECGSPAQ CEMSEWSPWG PCSKKRKLCGFRKGSEERTR RVLHAPGGDH TTCSDTKETR KCTVRRTPCP EGQKRRKGGQ GRRENANRHP ARKNSKEPGSNSRRHKGQQQ PQPGTTGPLT SVGPTWAQHH HHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation RSPO1 protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Introduction

R-Spondin-1(Rspo1) is a part of the Rspondin family. Rspo1 plays a role as an activator ofthe canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors.Rspo1 induces the onset of crypt cell proliferation and increases intestinalepithelial healing effect. Rspo1 is negatively regulating the TGF-beta pathway.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.