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Reuterin

(Synonyms: 罗氏菌素,3-Hydroxypropionaldehyde; 3-Hydroxypropanal) 目录号 : GC49790

Reuterin 是一种广谱抗菌剂,对革兰氏阳性菌和革兰氏阴性菌以及酵母菌、霉菌和原生动物具有活性。

规格 价格 库存 购买数量
25 mg
¥826.00
现货
50 mg
¥1,484.00
现货
100 mg
¥2,646.00
现货
250 mg
¥5,376.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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产品描述

Reuterin is a glycerol metabolite originally isolated from L. reuteri, a bacteria found in the intestines of humans, that has antibacterial activity.1 It is produced by L. reuteri during exposure to live or UV-killed E. coli.2 Reuterin is active against E. coli and several species of Bacteroides, Bifidobacterium, and Eubacterium (MICs = 1.9-15 mM) as well as C. difficile and B. vulgatus (MICs = <1.9 mM for both).3 It enhances increases in the production of reactive oxygen species (ROS) and cell death induced by vancomycin or metronidazole in C. difficile when used at a concentration of 2.5 mM.4 Reuterin alters the bacterial composition of, and volatile organic compounds (VOCs) produced by, the mouse fecal microbiome.5

1.Talarico, T.L., Casas, I.A., Chung, T.C., et al.Production and isolation of reuterin, a growth inhibitor produced by Lactobacillus reuteriAntimicrob. Agents Chemother.32(12)1854-1858(1988) 2.Schaefer, L., Auchtung, T.A., Hermans, K.E., et al.The antimicrobial compound reuterin (3-hydroxypropionaldehyde) induces oxidative stress via interaction with thiol groupsMicrobiology (Reading)156(Pt 6)1589-1599(2010) 3.Cleusix, V., Lacroix, C., Vollenweider, S., et al.Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteriaBMC Microbiol.7101(2007) 4.Engevik, M.A., Danhof, H.A., Shrestha, R., et al.Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generationGut Microbes12(1)1788898(2020) 5.Castellani, C., ObermÜller, B., Kienesberger, B., et al.Production, storage stability, and susceptibility testing of reuterin and its impact on the murine fecal microbiome and volatile organic compound profileFront. Microbiol.12699858(2021)

Chemical Properties

Cas No. 2134-29-4 SDF Download SDF
别名 罗氏菌素,3-Hydroxypropionaldehyde; 3-Hydroxypropanal
化学名 N/A
Canonical SMILES O=CCCO
分子式 C3H6O2 分子量 74.1
溶解度 DMF: 25 mg/mL,DMSO: 20 mg/mL,Ethanol: 16 mg/mL,PBS (pH 7.2): 5 mg/mL 储存条件 -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
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