Src(Src激酶)
Src (proto-oncogene tyrosine-protein kinase) is a non-receptor protein tyrosine kinase family including 9 members and promotes survival, angiogenesis, proliferation and invasion pathways.
Products for Src
- Cat.No. 产品名称 Information
- GC13600 WH-4-023 An inhibitor of Lck and Src
- GC17638 KB SRC 4 KB SRC 4 是一种有效的、高选择性的 c-Src 抑制剂,Ki 为 44 nM,Kd 为 86 nM,对 c-Abl 没有抑制作用,最高可达 125 μM; KB SRC 4 具有抗肿瘤活性。
- GC10775 MLR 1023 An allosteric Lyn kinase activator
- GC12958 ER 27319 maleate Syk激酶的选择性抑制剂
- GC16957 Src I1 A potent inhibitor of Src kinases
- GC11526 N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide Phosphopeptide for binding to the src SH2 domain
- GC12746 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu Phosphopeptide ligand for the src SH2 domain
- GC17137 pp60 c-src (521-533) (phosphorylated) Peptide corresponding to the pp60c-src carboxy terminal regulatory domain
- GC13797 PP 3 A negative control for Src tyrosine kinase inhibitors
- GC15211 Damnacanthal Damnacanthal 是一种从海巴戟根中分离出来的蒽醌。
- GC15000 Herbimycin A An inhibitor of tyrosine kinases and Hsp90
- GC10523 KX1-004 An inhibitor of Src-PTK
- GC17789 A 419259 trihydrochloride An inhibitor of Src family kinases
- GC11696 1-NM-PP1 Inhibitor of modified 'analog-sensitive' kinases
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GC14292
Apatinib Mesylate
A selective VEGFR2 inhibitor
- GC14007 DCC-2036 (Rebastinib) An orally bioavailable tyrosine kinase inhibitor
- GC11003 PP121 A potent dual inhibitor of tyrosine and phosphoinositide kinases
- GC14288 KX2-391 A Src kinase inhibitor
- GC13592 PD173955 A tyrosine kinase inhibitor
- GC12185 ZM 306416 A VEGF receptor kinase inhibitor
- GC14332 NVP-BHG712 A selective EphB4 kinase inhibitor
- GC10048 MNS An inhibitor of Src, Syk, and platelet aggregation
- GC12172 1-Naphthyl PP1 Inhibitor of modified ‘analog-sensitive’ kinases
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GC14807
Fingolimod (FTY720) HCl
Fingolimod (FTY720), an immunosuppressant agent, usually used in the treatment of multiple sclerosis, also has anticancer actions and can act as an HDACi (Histone deacetylase inhibitors)[1].
- GC14396 Ponatinib (AP24534) An inhibitor of native and mutant Bcr-Abl
- GC15197 Saracatinib (AZD0530) A dual inhibitor of c-Src and Abl
- GC17473 Pelitinib (EKB-569) An EGFR receptor tyrosine kinase inhibitor
- GC13410 Masitinib (AB1010) An inhibitor of c-Kit
- GC13343 Bosutinib (SKI-606) An inhibitor of Src and Abl kinases
- GC10344 PP 2 (AG 1879) A selective inhibitor of Src tyrosine kinases
- GC17990 PP 1 Potent, selective Src family tyrosine kinase inhibitor
- GC13102 XL228 A tyrosine kinase inhibitor
- GC11622 TG 100801 TG 100801 是一种前药,可通过在开发过程中的去酯化作用产生 TG 100572,以治疗年龄相关性黄斑变性。 TG 100572 是一种多靶点激酶抑制剂,可抑制受体酪氨酸激酶和 Src 激酶;对于 VEGFR1、VEGFR2、FGFR1、FGFR2、PDGFRβ、Fgr、Fyn、Hck、Lck、Lyn、Src、Yes , 分别。
- GC13117 Lck Inhibitor A selective inhibitor of lymphocyte-specific protein tyrosine kinase
- GC10222 KX2-391 dihydrochloride A Src kinase inhibitor
- GC16519 ENMD-2076 A multi-kinase inhibitor
- GC12145 ENMD-2076 L-(+)-Tartaric acid ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂,对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
- GC15568 Dasatinib (BMS-354825) An inhibitor of Abl and Src
- GN10633 Scutellarein A natural flavone with diverse biological activities