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Src(Src激酶)

Src (proto-oncogene tyrosine-protein kinase) is a non-receptor protein tyrosine kinase family including 9 members and promotes survival, angiogenesis, proliferation and invasion pathways.

Products for  Src

  1. Cat.No. 产品名称 Information
  2. GC13600 WH-4-023 An inhibitor of Lck and Src
  3. GC17638 KB SRC 4 KB SRC 4 是一种有效的、高选择性的 c-Src 抑制剂,Ki 为 44 nM,Kd 为 86 nM,对 c-Abl 没有抑制作用,最高可达 125 μM; KB SRC 4 具有抗肿瘤活性。
  4. GC10775 MLR 1023 An allosteric Lyn kinase activator
  5. GC12958 ER 27319 maleate Syk激酶的选择性抑制剂
  6. GC16957 Src I1 A potent inhibitor of Src kinases
  7. GC11526 N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide Phosphopeptide for binding to the src SH2 domain
  8. GC12746 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu Phosphopeptide ligand for the src SH2 domain
  9. GC17137 pp60 c-src (521-533) (phosphorylated) Peptide corresponding to the pp60c-src carboxy terminal regulatory domain
  10. GC13797 PP 3 A negative control for Src tyrosine kinase inhibitors
  11. GC15211 Damnacanthal Damnacanthal 是一种从海巴戟根中分离出来的蒽醌。
  12. GC15000 Herbimycin A An inhibitor of tyrosine kinases and Hsp90
  13. GC10523 KX1-004 An inhibitor of Src-PTK
  14. GC17789 A 419259 trihydrochloride An inhibitor of Src family kinases
  15. GC11696 1-NM-PP1 Inhibitor of modified 'analog-sensitive' kinases
  16. GC14292 Apatinib Mesylate

    A selective VEGFR2 inhibitor

  17. GC14007 DCC-2036 (Rebastinib) An orally bioavailable tyrosine kinase inhibitor
  18. GC11003 PP121 A potent dual inhibitor of tyrosine and phosphoinositide kinases
  19. GC14288 KX2-391 A Src kinase inhibitor
  20. GC13592 PD173955 A tyrosine kinase inhibitor
  21. GC12185 ZM 306416 A VEGF receptor kinase inhibitor
  22. GC14332 NVP-BHG712 A selective EphB4 kinase inhibitor
  23. GC10048 MNS An inhibitor of Src, Syk, and platelet aggregation
  24. GC12172 1-Naphthyl PP1 Inhibitor of modified ‘analog-sensitive’ kinases
  25. GC14807 Fingolimod (FTY720) HCl

    Fingolimod (FTY720), an immunosuppressant agent, usually used in the treatment of multiple sclerosis, also has anticancer actions and can act as an HDACi (Histone deacetylase inhibitors)[1].

  26. GC14396 Ponatinib (AP24534) An inhibitor of native and mutant Bcr-Abl
  27. GC15197 Saracatinib (AZD0530) A dual inhibitor of c-Src and Abl
  28. GC17473 Pelitinib (EKB-569) An EGFR receptor tyrosine kinase inhibitor
  29. GC13410 Masitinib (AB1010) An inhibitor of c-Kit
  30. GC13343 Bosutinib (SKI-606) An inhibitor of Src and Abl kinases
  31. GC10344 PP 2 (AG 1879) A selective inhibitor of Src tyrosine kinases
  32. GC17990 PP 1 Potent, selective Src family tyrosine kinase inhibitor
  33. GC13102 XL228 A tyrosine kinase inhibitor
  34. GC11622 TG 100801 TG 100801 是一种前药,可通过在开发过程中的去酯化作用产生 TG 100572,以治疗年龄相关性黄斑变性。 TG 100572 是一种多靶点激酶抑制剂,可抑制受体酪氨酸激酶和 Src 激酶;对于 VEGFR1、VEGFR2、FGFR1、FGFR2、PDGFRβ、Fgr、Fyn、Hck、Lck、Lyn、Src、Yes , 分别。
  35. GC13117 Lck Inhibitor A selective inhibitor of lymphocyte-specific protein tyrosine kinase
  36. GC10222 KX2-391 dihydrochloride A Src kinase inhibitor
  37. GC16519 ENMD-2076 A multi-kinase inhibitor
  38. GC12145 ENMD-2076 L-(+)-Tartaric acid ENMD-2076 L-(+)-Tartaric acid 是一种多靶点激酶抑制剂,对 Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1 的 IC50 为 1.86、14、58.2、15.9、92.7、70.8、56.4 nM , FGFR2, Src, PDGFRα, 分别。
  39. GC15568 Dasatinib (BMS-354825) An inhibitor of Abl and Src
  40. GN10633 Scutellarein A natural flavone with diverse biological activities

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