ALK

ALK (anaplastic lymphoma kinase) is a member of insulin receptor protein-tyrosine superfamily, functioning in embryonic development and involved in cell survival and cell fate.

Products for ALK

Cat.No. 产品名称 Information
GC12273 GSK1838705A An IGF-1R and IR inhibitor
GC14552 LDK378
色瑞替尼; LDK378
An ALK inhibitor
GC16580 LDN-193189
LDN 193189;LDN193189

An inhibitor of BMP receptors ALK1, ALK2, ALK3, and ALK6
GC17283 AP26113
Brigatinib analog
A potent ALK inhibitor
GC14349 SB525334
6-[2-(1,1-二甲基乙基)-5-(6-甲基-2-吡啶基)-1H-咪唑-4-基]喹喔啉
A potent inhibitor of TGF-β R1/ALK5 kinase
GC16694 TAE684 (NVP-TAE684)
TAE 684
A selective ALK inhibitor
GC14931 LDN193189 Hydrochloride
LDN 193189 hydrochloride; LDN-193189 hydrochloride
LDN193189 Hydrochloride是一种选择性转录活性形态发生蛋白（BMP）I型受体抑制剂，BMP受体家族包括激活素受体样激酶（ALK1、ALK2、ALK3和ALK6）。LDN193189 Hydrochloride抑制ALK2和ALK3的IC₅₀值分别为5nM和30nM。
GC17452 LDK378 dihydrochloride
双盐酸盐色瑞替尼; LDK378 dihydrochloride
LDK378 dihydrochloride (LDK378 dihydrochloride) 是一种选择性、口服生物利用度和 ATP 竞争性的 ALK 酪氨酸激酶抑制剂，IC50 为 200 pM。
GC14446 ASP3026
ASP 3026;ASP-3026
An ALK inhibitor
GC17376 ALK inhibitor 2
2-[[5-氯-2-[[2-甲氧基-4-(4-甲基-1-哌嗪基)苯基]氨基]-4-嘧啶基]氨基]-N-甲基苯磺酰胺
An inhibitor of TSSK2
GC14729 (R)-Crizotinib
克唑替尼; PF-02341066
A c-MET and ALK receptor tyrosine kinase inhibitor