PKC(蛋白激酶C)

PKC (protein kinase C) is a serine/threonine protein kinase that mediates insulin signaling, actin cytoskeleton, cell mobility, apoptosis and tumorigenesis etc.

Products for PKC

Cat.No. 产品名称 Information
GC13677 Ro 32-0432 hydrochloride Ro 32-0432 hydrochloride 是一种有效的、选择性的、ATP 竞争性和口服活性的 PKC 抑制剂。
GC17346 KT 5823 Potent selective inhibitor of cGMP-dependent protein kinase (PKG)
GC17767 Dihydrosphingosine A mixture of sphingolipid pathway intermediates
GC17591 D-erythro-Sphingosine (synthetic) A pharmacological tool to probe the activity of protein kinase C
GC13890 (±)-Palmitoylcarnitine chloride A long-chain acylcarnitine with intracellular and extracellular roles
GC10496 Midostaurin (PKC412) Kinase inhibitor with potential use in cancer treatment
GC13869 Fasudil Fasudil (HA-1077; AT877) 是一种非特异性 RhoA/ROCK 抑制剂，对蛋白激酶也有抑制作用，对 ROCK1 的 Ki 为 0.33 μM，对 ROCK2 和 PKA 的 IC50 分别为 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM ，PKC，PKG，分别。 Fasudil 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。
GC16934 Valrubicin A semisynthetic anthracycline antitumor antibiotic
GC13461 ZIP (SCRAMBLED) ZIP (SCRAMBLED) 是 zeta 抑制肽 (ZIP) 的乱序对照肽。
GC14363 Mitoxantrone HCl An inhibitor of DNA topoisomerase IIα and HIV-1 integrase
GC16354 Dequalinium Chloride An ammonium cation with diverse biological activities
GC17322 Ro 31-8220 Ro 31-8220 是一种有效的 PKC 抑制剂，对 PKCα、PKCβI、PKCβII、PKCγ、PKCε 和大鼠脑 PKC 的 IC50 分别为 5、24、14、27、24 和 23 nM。
GC13232 Verbascoside A natural phenylpropanoid glucoside with diverse biological activities
GC15420 ICP 103 Protein kinase inhibitor
GC15520 Sotrastaurin (AEB071) A PKC and GSK3 inhibitor
GC15281 K-252c A cell-permeable PKC inhibitor
GC16907 Go 6983 Inhibitor of protein kinase C
GC15431 GF 109203X (Bisindolylmaleimide I) A PKC inhibitor
GC15564 Go 6976 A PKCα/β1 inhibitor
GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM 分别代表 ROCK2 和 PKA、PKC、PKG。 Fasudil (HA-1077) HCl 也是一种有效的 Ca2+ 通道拮抗剂和血管扩张剂。
GC14701 Zoledronic Acid A bisphosphonate that inhibits bone resorption
GC11499 Enzastaurin (LY317615) An inhibitor of PKC and Akt signaling
GC16584 TCS 21311 A JAK3 inhibitor
GC13065 Chelerythrine Chloride Potent inhibitor of PKC and Bcl-xL
GC14650 CGP60474 A CDK inhibitor
GN10444 12-O-tetradecanoyl phorbol-13-acetate
一种PKC激活剂
GN10336 Daphnetin A coumarin derivative with diverse biological activities
GN10463 Chelerythrine Chelerythrine 是一种天然生物碱，是一种有效的选择性 Ca2+/磷脂依赖性 PKC 拮抗剂，IC50 为 0.7 μM。
GC15299 Staurosporine(CGP 41251) A potent inhibitor of protein kinase C
GC14049 (-)-Epigallocatechin gallate (EGCG) (-)-Epigallocatechin Gallate sulfate (EGCG) 是绿茶中的一种主要多酚,可抑制细胞增殖并诱导细胞凋亡。此外,它还能抑制谷氨酸脱氢酶1/2 (GDH1/2, GLUD1/2)的活性。.