Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways >> Proteases >> Drug Metabolite

Drug Metabolite(药物代谢物)

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products for  Drug Metabolite

  1. Cat.No. 产品名称 Information
  2. GC49147 Carboxyphosphamide An inactive metabolite of cyclophosphamide
  3. GC49133 N-hydroxy Riluzole A metabolite of riluzole
  4. GC49131 Dehydro Warfarin A metabolite of (±)-warfarin
  5. GC49130 Hydroxy Celecoxib An inactive metabolite of celecoxib
  6. GC49127 4-oxo Cyclophosphamide An inactive metabolite of cyclophosphamide
  7. GC49119 5-hydroxy Flunixin A metabolite of flunixin
  8. GC49118 10-hydroxy Warfarin

    A metabolite of (R)-warfarin
  9. GC49115 Desacetylcefotaxime (potassium salt) An active metabolite of cefotaxime
  10. GC49111 Carbamazepine 10,11-epoxide An active metabolite of carbamazepine
  11. GC49100 Desmethyl Ofloxacin (hydrochloride) A metabolite of ofloxacin
  12. GC49051 7-hydroxy Methotrexate A metabolite of methotrexate
  13. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
  14. GC48979 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate) A substrate of multidrug resistance protein 2
  15. GC62481 AST5902 trimesylate AST5902 is the principal metabolite of alflutinib both in vitro and in vivo, which exerts remarkable antineoplastic activity similar to alflutinib. AST5902 exhibits much weak CYP3A4 induction potential compared to alflutinib.
  16. GC62278 FTISADTSK acetate FTISADTSK acetate 是一种内源性稳定的曲妥珠单抗信号肽，由SRM监测得到。
  17. GC62152 Homovanillyl alcohol Homovanillyl alcohol 是羟基酪醇的生物代谢产物。Hydroxytyrosol 是原始橄榄油 (VOO) 和葡萄酒中存在的一种酚类化合物。Homovanillyl alcohol 可保护红细胞 (RBCs) 免受氧化损伤，并对心血管疾病具有保护作用。
  18. GC61864 DL-Laudanosine DL-Laudanosine 是 Atracurium 和 Cisatracurium 的代谢物，可透过血脑屏障，引起兴奋和癫痫发作。
  19. GC61813 O-Desmethyl Mebeverine alcohol hydrochloride O-DesmethylMebeverinealcoholhydrochloride是Mebeverine的代谢物，Mebeverine是一种有效的α1受体(α1repector)抑制剂，用作消化道的一种解痉药。
  20. GC61536 Beclomethasone 17-propionate Beclomethasone17-propionate(Beclomethasone-17-monopropionate)是Beclomethasonedipropionate的活性代谢产物，是糖皮质激素受体(GR)激动剂。Beclomethasone17-propionate对GR的亲和力比Beclomethasonedipropionate高。Beclomethasone17-propionate有效抑制慢性阻塞性肺疾病(COPD)肺巨噬细胞中细胞因子的产生。
  21. GC61478 N-Desmethyl Pimavanserin N-DesmethylPimavanserin是Pimavanserin的活性代谢物。Pimavanserin是选择性的5-HT2A受体反向激动剂，pIC50和pKd分别为8.73和9.3。
  22. GC48804 N-desmethyl Olanzapine A major metabolite of olanzapine
  23. GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin
  24. GC48720 Griseofulvic Acid A metabolite of griseofulvin
  25. GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine
  26. GC48611 Ambroxol-d5 An internal standard for the quantification of ambroxol
  27. GC48493 PCI 45227 An active metabolite of ibrutinib
  28. GC48461 rac-trans-4-hydroxy Glyburide An active metabolite of glyburide
  29. GC48457 3-keto Fusidic Acid An active metabolite of fusidic acid
  30. GC47923 Paraxanthine-d6 An internal standard for the quantification of paraxanthine
  31. GC47757 N-Desmethylclozapine-d8 An internal standard for the quantification of N-desmethylclozapine
  32. GC47756 N-desmethyl Rosuvastatin (sodium salt hydrate) An active metabolite of rosuvastatin
  33. GC47746 NAP 226-90 A metabolite of rivastigmine
  34. GC47735 N-acetyl Desethylchloroquine-d4 An internal standard for the quantification of N-acetyl desethylchloroquine
  35. GC47320 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate) A metabolite of ethynyl estradiol
  36. GC47195 Desethylchloroquine-d4 An internal standard for the quantification of desethylchloroquine
  37. GC47193 Desethyl Hydroxychloroquine-d4 An internal standard for the quantification of desethyl hydroxychloroquine
  38. GC47040 Carebastine-d5 An internal standard for the quantification of carebastine
  39. GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide
  40. GC46539 2-Chloroadenine A heterocyclic building block
  41. GC46508 2',2'-Difluoro-2'-deoxyuridine An active metabolite of gemcitabine
  42. GC46387 1,3,7-Trimethyluric Acid-d9 An internal standard for the quantification of 1,3,7-trimethyluric acid
  43. GC46284 (±)-Cotinine-d3 An internal standard for the quantification of cotinine
  44. GC61353 Trimethoprim N-oxide TrimethoprimN-oxide(Trimethoprim1-N-oxide)属于人尿代谢物。TrimethoprimN-oxide是通过氧化嘧啶环中的氮原子生成的。TrimethoprimN-oxide主要由CYP1A2在人肝微粒体中形成。
  45. GC61182 Phosphoramide mustard (cyclohexanamine) An alkylating agent and active metabolite of cyclophosphamide
  46. GC61165 Paeoniflorgenin Paeoniflorgenin是Paeoniflorin的去糖基化代谢产物。
  47. GC61147 O-desmethyl Mebeverine acid A metabolite of mebeverine
  48. GC61137 Nordoxepin D3 hydrochloride NordoxepinD3hydrochloride(DesmethyldoxepinD3hydrochloride)是Nordoxepinhydrochloride的氘代物。Nordoxepinhydrochloride是Doxepinhydrochloride的活性代谢产物，Doxepinhydrochloride具有口服活性和抗抑郁作用。
  49. GC61115 N-Desethyl Oxybutynin D5 hydrochloride N-DesethylOxybutyninD5hydrochloride是N-DesethylOxybutyninhydrochloride的氘代物。N-DesethylOxybutynin是Oxybutynin的活性代谢产物。Oxybutynin是一种抗胆碱能药，抑制电压依赖型K+通道。
  50. GC61037 Mebeverine acid A metabolite of mebeverine
  51. GC60920 Hydroxyhexamide Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide, which is a sulfonylurea hypoglycemic agent.

Items 151 to 200 of 452 total

per page
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6

Set Descending Direction