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SPHK(鞘氨醇激酶)

SPHK (sphingosine kinase) is a conserved lipid kinase that catalyzes formation S1P (sphingosine-1-phosphate) from the precursor sphingolipid sphingosine.

  1. Cat.No. 产品名称 Information
  2. GN10444 12-O-tetradecanoyl phorbol-13-acetate

    A PKC activator

  3. GC10154 ABC294640 An inhibitor of SPHK2
  4. GC12581 K145 A selective SPHK2 inhibitor
  5. GC36372 K145 hydrochloride A selective SPHK2 inhibitor
  6. GC19501 MHP MHP (Methyl caprooyl tyrosinate) 是鞘氨醇激酶 (SPHK1) 的激活剂,可显着刺激 CAMP mRNA 和蛋白质的产生。
  7. GC33016 MP-A08 An inhibitor of SPHK1 and SPHK2
  8. GC32107 Peretinoin (NIK333)
  9. GC50253 PF 543 hydrochloride A potent inhibitor of SPHK1
  10. GC11917 PF-543 A potent inhibitor of SPHK1
  11. GC16352 PF-543 Citrate PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) 是一种有效的、选择性的、可逆的和鞘氨醇竞争性的 SPHK1 抑制剂,IC50 为 2 nM,Ki 为 3.6 nM。
  12. GC61597 SK1-I
  13. GC33836 SK1-IN-1
  14. GC44896 SKI 178 A non-selective inhibitor of SPHK1 and SPHK2
  15. GC16701 SKI II An SPHK1 inhibitor
  16. GC60339 SKI V SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.
  17. GC66011 SKI-I

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