Phospholipase(磷脂酶)
Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.
Products for Phospholipase
- Cat.No. 产品名称 Information
- GC42029 1-Palmitoyl-2-linoleoyl PE A product of lipid biosynthesis
- GC41808 1,2-Dioctanoyl PC A short chain analog of phosphatidylcholine
- GC41782 1,2-bis(heptanoylthio) Glycerophosphocholine A substrate for PLA2s
- GC41004 Rhamnetin A flavonoid with diverse biological activities
- GC40794 Sphinganine (d18:0) Sphingolipid pathway intermediate
- GC40679 (S)-Bromoenol lactone A selective iPLA2β inhibitor
- GC40678 (R)-Bromoenol lactone A selective iPLA2γ inhibitor
- GC40545 cis-Parinaric Acid A naturally-occurring PUFA
- GC33457 1-Naphthaleneacetic acid (1-Naphthylacetic acid) 1-Naphthaleneacetic acid (α-Naphthaleneacetic acid) is a synthetic plant hormone in the auxin family.
- GC32768 Quinacrine dihydrochloride (Mepacrine dihydrochloride) Quinacrine是一种荧光探针,使胆碱能受体蛋白发生构象转变,低μM水平对AML细胞具有作用活性,平均IC50为2.30μM。
- GC32224 Lp-PLA2 -IN-1 Lp-PLA2-IN-1可以抑制beta-lactamase-IN-1的活性,例如动脉粥样硬化,阿尔茨海默氏症。
- GC31825 Varespladib methyl (A-002) Varespladibmethyl (A-002) (A-002; LY333013) 是 II 组分泌型磷脂酶 A2 (PLA2) 的选择性抑制剂。
- GC31355 AA26-9 A pan-serine hydrolase inhibitor
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GC30610
LY 178002
LY178002是一种有效的5-lipoxygenase,phospholipaseA2抑制剂,对5-lipoxygenase的IC50值为0.6μM,能够抑制人多形核白细胞产生LTB4,同时可相对较弱地抑制cyclooxygenase的活性。
- GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂,可以在压力引起的溃疡大鼠中,维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。
- GC30464 Ecopladib (PLA 725) Ecopladib (PLA 725) 是细胞溶质磷脂酶 A2α 的亚微摩尔抑制剂; (cPLA2α),在 GLU 胶束和大鼠全血试验中,IC50 分别为 0.15 μM 和 0.11 μM。
- GC30180 ST271 ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity.
- GC11055 10-Pyrene-PC A substrate for some PLA2s
- GC19186 GW4869 Inhibitor of neutral sphingomyelinase
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GC18691
CAY10594
Potent and selective PLD2 inhibitor
- GC18559 Lysophosphatidylethanolamines (egg) A mixture of lysophosphatidylethanolamines isolated from egg
- GC18305 CAY10650 Potent cPLA2α inhibitor
- GC11520 ST638 Tyrosine kinase inhibitor
- GC14521 ONO-RS-082 A PLA2 inhibitor
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GC10645
MJ33 (lithium salt)
An inhibitor of the PLA2 activity of Prdx6
- GC18141 EA4 An inhibitor of PLA2 from red blood cells
- GC11116 Thioetheramide-PC A competitive, reversible inhibitor of sPLA2
- GC11243 Halopemide Inhibitor of phospholipase D1 and D2
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GC13276
Oleyloxyethyl Phosphorylcholine
A PLA2 inhibitor
- GC16770 Arachidonic Acid Leelamide A novel fatty acid amide
- GC13351 VU0359595 A selective PLD1 inhibitor
- GC11021 Bromoenol lactone A selective, potent, irreversible inhibitor of iPLA2
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GC10565
7-hydroxycoumarinyl Arachidonate
A substrate for cPLA2
- GC13930 N-(p-amylcinnamoyl) Anthranilic Acid A TRP channel blocker and PLA2 inhibitor
- GC17889 ML 349 A selective and reversible inhibitor of LYPLA2
- GC18039 ML 348 A selective LYPLA1 inhibitor
- GC10162 JJKK 048 JJKK 048 是一种超强效和高选择性的单酰基甘油脂肪酶 (MAGL) 抑制剂。
- GC11073 ML 298 hydrochloride A selective inhibitor of PLD2
- GC13948 GPi 688 GPi 688 是一种有效且具有口服活性的糖原磷酸化酶 (GPa) 抑制剂,对人肝 GPa、大鼠肝 GPa 和人骨骼肌 GPa 的 IC50 分别为 19 nM、61 nM 和 12 nM。
- GC15877 CP 316819 An inhibitor of glycogen phosphorylase A
- GC17684 VU 0364739 hydrochloride phospholipase D2 (PLD2) inhibitor
- GC13620 FIPI Potent inhibitor of PLD1 and PLD2
- GC15888 VU 0155069 Selective inhibitor of phospholipase D1
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GC16115
AACOCF3
An inhibitor of cPLA2 and iPLA2
- GC17420 OBAA OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂,IC50 为 70 nM。
- GC16364 LY 311727 An inhibitor of Group IIA sPLA2
- GC16687 Edelfosine Edelfosine ((R)-ET-18-OCH3) 是一种醚脂质类似物,具有抗 HIV 和抗肿瘤活性。
- GC13585 YM 26734 A group IIA sPLA2 inhibitor
- GC14090 o-3M3FBS An inactive analog of m-3M3FBS
- GC16286 m-3M3FBS An activator of phospholipase C