PDE(磷酸二酯酶)

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Products for PDE

Cat.No. 产品名称 Information
GC11472 AN-2728 A selective PDE4 inhibitor
GC11273 Anagrelide HCl A PDE3 inhibitor
GC10077 S- (+)-Rolipram S- (+)-Rolipram ((+)-Rolipram) 是一种环状 AMP(cAMP) 特异性磷酸二酯酶 4 (PDE4) 抑制剂，IC50 为 1100 nM。
GC12764 Aminophylline A phosphodiesterase inhibitor and adenosine receptor antagonist
GC13652 Dyphylline An adenosine receptor antagonist and phosphodiesterase inhibitor
GC12808 Pimobendan An inhibitor of PDE3
GC15890 Cilostazol A PDE3A inhibitor
GC16856 Avanafil A potent and selective PDE5 inhibitor
GC14180 GSK256066 A potent PDE4 inhibitor
GC17598 Cilomilast A PDE4 inhibitor
GC16629 Rolipram A phosphodiesterase-4 inhibitor
GC17074 Tadalafil A PDE5 inhibitor
GC15194 PF-2545920 A potent inhibitor of PDE10A
GC10588 Vardenafil HCl Trihydrate An inhibitor of PDE5 and PDE6
GC17685 Sildenafil Citrate A PDE5 inhibitor
GC16347 Roflumilast A PDE4 inhibitor
GC10420 Apremilast (CC-10004) An orally available PDE4 inhibitor
GN10231 Fraxin A coumarin glycoside
GN10278 Icariin
Icariin is a flavonol glycoside.
GN10659 Theophylline A phosphodiesterase inhibitor and adenosine receptor antagonist