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Home >> Signaling Pathways >> Metabolism >> PDE

PDE(磷酸二酯酶)

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Products for  PDE

  1. Cat.No. 产品名称 Information
  2. GC13275 Ibudilast An inhibitor of PDE4
  3. GC11125 Sp-Cyclic AMPS (sodium salt) A cAMP derivative
  4. GC16072 ML-030 A selective inhibitor of PDE4A
  5. GC13956 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide An inhibitor of PDE7
  6. GC11782 Ophiobolin A A calmodulin antagonist
  7. GC10796 Eggmanone A selective phosphodiesterase 4 inhibitor
  8. GC16849 MBCQ An inhibitor of PDE5
  9. GC10859 Amino Tadalafil An analog of tadalafil
  10. GC15037 Sildenafil mesylate A PDE5 inhibitor
  11. GC17999 TC-E 5005 PDE10A inhibitor
  12. GC13121 Piclamilast A PDE4 inhibitor
  13. GC11789 T 0156 hydrochloride T 0156 hydrochloride 是一种有效的选择性 5 型磷酸二酯酶 (PDE5) 抑制剂。
  14. GC16048 BC 11-38 A potent and selective PDE11 inhibitor
  15. GC14697 HA 130 A reversible autotaxin inhibitor
  16. GC15189 Gisadenafil besylate A PDE5 inhibitor
  17. GC16632 CDP 840 hydrochloride CDP 840 hydrochloride (GR259653X) 是一种有效的、选择性的和口服活性的磷酸二酯酶 IV (PDE IV) 抑制剂。
  18. GC15475 RS 25344 hydrochloride RS 25344 hydrochloride 是一种选择性 cAMP-磷酸二酯酶 4 (PDE 4; PDE IV) 抑制剂，对人淋巴细胞的 IC50 为 0.28 nM。
  19. GC13657 Mesopram PDE4 inhibitor, orally active
  20. GC10542 CP 80633 Inhibitor of phosphodiesterase type 4
  21. GC15472 BRL 50481 A potent, selective inhibitor of PDE7
  22. GC12059 YM 976 A PDE4 inhibitor
  23. GC11313 ICI 63197 A PDE3 and PDE4 inhibitor
  24. GC10004 Enoximone A PDE3 inhibitor
  25. GC14398 Siguazodan Siguazodan (SKF 94836) 是一种有效的、选择性的、具有口服活性的磷酸二酯酶 III (PDE-III) 抑制剂，IC50 为 117 nM。
  26. GC10109 Cilostamide A selective inhibitor of PDE3
  27. GC12878 MMPX calmodulin-sensitive cyclic GMP phosphodiesterase inhibitor
  28. GC12771 Etazolate hydrochloride PDE-4 inhibitor and selective GABA-A receptor modulator
  29. GC11684 MY-5445 A PDE5 inhibitor
  30. GC11730 IBMX Non-specific inhibitor of cAMP and cGMP phosphodiesterases
  31. GC13495 Trequinsin hydrochloride An inhibitor of PDE3
  32. GC12909 Zaprinast A cGMP phosphodiesterase inhibitor
  33. GC13842 Ro 20-1724 A selective PDE4 inhibitor
  34. GC12824 Dibutyryl-cAMP, sodium salt A cell-permeable, cAMP analog
  35. GC13287 Udenafil A PDE5 inhibitor
  36. GC13191 Irsogladine A gastroprotective agent
  37. GC17673 Dipyridamole A PDE5A inhibitor
  38. GC13444 Doxofylline A bronchodilator
  39. GC17422 Pimobendan hydrochloride An inhibitor of PDE3
  40. GC12060 Deltarasin hydrochloride A KRAS inhibitor
  41. GC14868 Milrinone An inhibitor of PDE3
  42. GC16658 Vinpocetine An inhibitor of PDE1
  43. GC15242 Vardenafil Vardenafil 是一种具有口服活性的选择性磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 0.7 nM。
  44. GC10944 Butein A plant polyphenol
  45. GC16426 Zardaverine A dual inhibitor of PDE3 and PDE4
  46. GC11369 Sildenafil

    A PDE5 inhibitor
  47. GC14510 PF-8380 An inhibitor of autotaxin
  48. GC10648 PF-04447943 A PDE9A inhibitor
  49. GC17221 Olprinone Hydrochloride An inhibitor of PDE3
  50. GC11072 Nortadalafil 诺他达拉非是去甲基他达拉非，它是一种 PDE5 抑制剂，目前以药丸形式销售，用于治疗勃起功能障碍 (ED)，名称为 Cialis；并以 Adcirca 的名义用于治疗肺动脉高压。
  51. GC13076 Deltarasin A KRAS inhibitor

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