MEK1/2
MEK1/2, also known as MAPKK (mitogen-activated protein kinase kinase), is a kinase enzyme which phosphorylates MAPK (mitogen-activated protein kinase).
- Cat.No. 产品名称 Information
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GC64904
MAP855
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GC64292
MS432
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GC63554
PD0325901-O-C2-dioxolane
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GC63264
Zapnometinib
Zapnometinib (PD0184264, ATR-002), an major active metabolite of CI-1040, is a novel MEK inhibitor with an IC50 of 5.7 nM.
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GC38653
Selumetinib sulfate
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GC37523
RGB-286638 free base
A multi-kinase inhibitor
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GC37522
RGB-286638
A multi-kinase inhibitor
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GC37516
Refametinib R enantiomer
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GC36199
GW284543
GW284543 (UNC10225170), a MEK5-selective inhibitor, inhibits MEK5 in a dose-dependently way as determined by reductions in pERK5, and decreases endogenous MYC protein.
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GC35719
Cobimetinib hemifumarate
A potent, orally available MEK1 inhibitor
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GC35684
CHMFL-EGFR-202
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GC45099
U-0126
A MEK inhibitor and AMPK activator
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GC43885
Hypothemycin
A resorcylic acid lactone polyketide with diverse biological activities
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GC41573
Theaflavin 3,3'-digallate
A polyphenol with diverse biological activities
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GC33831
Lidocaine hydrochloride (Lignocaine hydrochloride)
An Analytical Reference Standard
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GC33388
MEK-IN-1
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GC33305
Balamapimod (MKI 833)
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GC30162
trans-Zeatin
A cytokinin plant growth regulator
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GC15646
PD 184161
A potent MEK1/2 inhibitor
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GC15240
APS-2-79
An inhibitor of KSR-dependent MAPK signaling
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GC17828
BI-847325
A selective dual MEK/Aurora kinase inhibitor
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GC14647
SCH772984 HCl
A selective inhibitor of ERK1/2
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GC15044
SCH772984 TFA
A selective inhibitor of ERK1/2
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GC12406
RO5126766(CH5126766)
A dual inhibitor of MEK1 and Raf kinases
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GC12006
GDC-0994
A selective ERK1/2 inhibitor
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GC17485
PD 334581
A MEK inhibitor
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GC12851
10Z-Hymenialdisine
A natural alkaloid that inhibits MEK-1 and other kinases
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GC17964
PD 198306
A potent inhibitor of MEK1/2
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GC15061
U0124
An inactive analog of U-0126
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GC14247
GDC-0623
A potent, ATP-uncompetitive inhibitor of MEK1
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GC16872
Refametinib
An allosteric inhibitor of MEK1/2
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GC10209
TAK-733
A MEK1 inhibitor
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GC12141
RO4987655
A MEK inhibitor
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GC14643
AZD8330
A MEK1/2 inhibitor
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GC12843
MEK162 (ARRY-162, ARRY-438162)
A MEK1/2 inhibitor
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GC15693
BIX 02188
A potent MEK5 inhibitor
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GC12220
BIX 02189
An inhibitor of MEK5 and ERK5
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GC10110
PD318088
An allosteric inhibitor of MEK1
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GC18050
Pimasertib (AS-703026)
A MEK1/2 inhibitor
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GC12989
PD184352 (CI-1040)
A potent MEK inhibitor
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GC15359
SL-327
A selective MEK1/2 inhibitor
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GC12819
PD98059
A MAPK pathway inhibitor and AMPK activator
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GC17608
Lidocaine
An Analytical Reference Standard
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GC17030
AZD6244(Selumetinib)
A highly selective inhibitor of MEK1/2
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GC15260
Trametinib DMSO solvate
Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) 是一种具有口服活性的 MEK 抑制剂,抑制 MEK1 和 MEK2,IC50 约为 2 nM。 Trametinib DMSO solvate 激活自噬并诱导细胞凋亡。
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GC16001
SCH772984
A selective inhibitor of ERK1/2
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GC11277
MEK inhibitor
MEK 抑制剂是一种有效的 MEK 抑制剂,具有抗肿瘤效力。
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GC14337
Cobimetinib (R-enantiomer)
Cobimetinib R-对映异构体是 Cobimetinib 活性较低的 R-对映异构体。 Cobimetinib 是一种有效的选择性 MEK 抑制剂。
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GC17426
Cobimetinib (racemate)
Cobimetinib(消旋体)(GDC-0973 消旋体;XL518 消旋体)是 Cobimetinib 的消旋体。 Cobimetinib 是一种有效的选择性 MEK 抑制剂。
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GC10033
Cobimetinib
A potent, orally available MEK1 inhibitor