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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

Potassium Channel(钾离子通道)

Potassium channels are voltage-gated ion channels that selectively permeate potassium ion through the excitable membrane. It regulates the release of neurotransmitters, insulin secretion, smooth muscle contraction and heart rate etc.

Products for  Potassium Channel

  1. Cat.No. 产品名称 Information
  2. GC18629 VU0071063 A Kir6.2/SUR1 activator
  3. GC18210 GAL-021 A BKCa channel blocker
  4. GC18203 Annonacin A mitochondrial complex I inhibitor
  5. GC15117 ML-297 A selective GIRK1/2 activator
  6. GC11351 VU590 (hydrochloride) inhibitor of KCNJ1
  7. GC17001 Verruculogen A tremorgenic mycotoxin
  8. GC10497 Hexachlorophene KCNQ1/KCNE1 potassium channel activator
  9. GC13490 E-4031 An antiarrhythmic, ERG potassium channel blocker
  10. GC13353 Spadin An inhibitor of K2P2.1/TREK1
  11. GC14029 Retigabine An Analytical Reference Standard
  12. GC14705 Tolbutamide Sodium A SUR1/Kir6.2 channel inhibitor
  13. GC14515 Azimilide A class III antiarrhythmic agent
  14. GC10560 ICA 110381 ICA 110381 (Compound 16) 是一种 KCNQ2/Q3 钾通道开放剂，用于治疗癫痫。
  15. GC17909 NS 6180 An inhibitor of IKCa1/KCa3.1 channels
  16. GC10540 NS 11021 A BKCa channel opener
  17. GC11061 ML 213 A selective activator of KCNQ2 and KCNQ4 channels
  18. GC15855 NS 3623 An ion channel modulator
  19. GC13455 VU 591 hydrochloride VU 591 hydrochloride 是一种有效的、选择性的肾外髓质钾通道 (ROMK 或 Kir1.1) 抑制剂，IC50 为 0.24 μM。
  20. GC16095 MaxiPost A KCa1.1/BK channel activator
  21. GC10492 ML 277 An activator of KCNQ1
  22. GC16502 Psora 4 An inhibitor of Kv1.3 channels
  23. GC10352 GW 542573X Activator of small-conductance Ca2+-activated K+ channels (KCa2)
  24. GC16447 ICA 069673 A Kv7 channel activator
  25. GC17280 NS 5806 An Ito current activator
  26. GC11550 JNJ 303 An inhibitor of Kv7.1
  27. GC15369 VU 590 dihydrochloride VU 590 dihydrochloride 是一种有效且具有中等选择性的 ROMK (Kir1.1) 抑制剂，IC50 为 290 nM。
  28. GC17787 UK 78282 hydrochloride KV1.3 and KV1.4 voltage-gated potassium channel blocker
  29. GC10094 BL 1249 BL 1249 是一种非甾体抗炎药 (NSAID) 和钾通道激活剂。
  30. GC12140 Endoxifen Endoxifen Z-异构体是最重要的他莫昔芬代谢物，负责在表达雌激素受体-α (ERα) 的乳腺癌细胞中引发该药物的抗雌激素作用。
  31. GC14790 SKA 31 An activator of KCa2/3 channels
  32. GC16948 Valinomycin Valinomycin是一种具有钾选择性离子活性的环沉积肽抗生素。它可以作为解偶联剂来诱导去极化。.
  33. GC12424 NS 1643 An activator of ERG1 and ERG2
  34. GC16144 CyPPA A positive modulator of SK2 and SK3
  35. GC10182 PD 118057 PD 118057 是一种 hERG 通道激活剂，不会导致 hERG 阻断。
  36. GC14239 BMS 191011 A KCa1.1/BK channel activator
  37. GC13188 UCL 2077 UCL 2077 是一种选择性慢后超极化 (sAHP) 通道阻滞剂（在培养的海马神经元中 IC50 =500 nM），对超极化后的 Ca2+ 通道、动作电位、输入电阻和介质影响最小。
  38. GC11421 L-364,373 L-364,373 (R-L3) 是一种电压门控 Kv7.1 (KCNQ1)/水貂通道激活剂。
  39. GC12575 DPO-1 An inhibitor of Kv1.5 channels
  40. GC11429 DMP 543 An inhibitor of Kv7.2
  41. GC17739 PNU 37883 hydrochloride PNU 37883 hydrochloride (PNU 37883A) 是一种选择性血管 ATP 敏感性钾 (Kir6, KATP) 通道阻滞剂。
  42. GC16690 Y-27152 Y-27152 是 KATP (Kir6) 通道开放剂 Y-26763 的前药，是一种长效的 K+ 通道开放剂，具有较少的心动过速:对清醒状态的高血压大鼠和狗的抗高血压作用。
  43. GC11132 Y-26763 An activator of KATP channels
  44. GC11919 XE 991 dihydrochloride A blocker of KCNQ channels
  45. GC14754 Linopirdine dihydrochloride A neurotransmitter release enhancer
  46. GC17661 E-4031 dihydrochloride An antiarrhythmic, ERG potassium channel blocker
  47. GC14073 DCPIB A VRAC inhibitor
  48. GC14044 (-)-[3R,4S]-Chromanol 293B (-)-[3R,4S]-Chromanol 293B 是延迟整流器 K+ 电流 (IKs) 的慢速成分的有效选择性抑制剂。
  49. GC15750 DCEBIO An activator of IKCa1/KCa3.1 channels
  50. GC10213 Chromanol 293B An IKs and ICTFR blocker
  51. GC17595 CP 339818 hydrochloride KV1.3 channel antagonist

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