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Home >> Signaling Pathways >> Endocrinology and Hormones >> Estrogen/progestogen Receptor

Estrogen/progestogen Receptor(雌激素/孕激素受体)

The estrogen/progestogen receptors are activated by the hormone estrogen/progesterone and regulate the gene transcription.

Products for  Estrogen/progestogen Receptor

  1. Cat.No. 产品名称 Information
  2. GC43631 Estrone 3-sulfate (sodium salt)

    A steroid
  3. GC43629 Estradiol 3-sulfate 17β-Glucuronide (potassium salt) A metabolite of estradiol 3-sulfate
  4. GC42473 4-tert-Octylphenol diethoxylate An endocrine disruptor
  5. GC41950 16α-hydroxy Estrone A hydroxylated metabolite of estrone
  6. GC41671 (±)-Equol 4'-sulfate (sodium salt) A metabolite of (±)-equol
  7. GC41300 17β-hydroxy Exemestane An active metabolite of exemestane
  8. GC41266 Pregnanediol-3-Glucuronide A metabolite of progesterone
  9. GC40833 (E/Z)-Endoxifen An active metabolite of tamoxifen
  10. GC40301 Tamoxifen N-oxide A metabolite of tamoxifen
  11. GC18641 Ferutinin An ERα agonist
  12. GC18635 18-hydroxy-11-deoxy Corticosterone A mineralocorticoid
  13. GC18462 3-Formylsalicylic Acid An inhibitor of estrone sulfatase
  14. GC18333 Equilenin An equine estrogen
  15. GC10002 Coumestrol A naturally-occurring phytoestrogen
  16. GC10684 Zearalanone A mycotoxin with estrogen-like effects
  17. GC17588 Bavachin A phytoestrogen
  18. GC11425 Lasofoxifene (tartrate) A selective estrogen receptor modulator
  19. GC16719 Ormeloxifene

    estrogen receptor modulator
  20. GC13917 4’-hydroxy Tamoxifen An active tamoxifen metabolite
  21. GC17119 8-Prenylnaringenin A phytoestrogen
  22. GC12644 Quinestrol

    A synthetic estrogen
  23. GC10663 Dihydrodaidzein An active metabolite of daidzein
  24. GC11606 4-Methylbenzylidene camphor A UV blocker with estrogenic effects
  25. GC11734 α-Zearalenol A major hepatic metabolite of zearalenone
  26. GC17161 Methylpiperidino pyrazole A specific estrogen receptor α antagonist
  27. GC14405 AZD9496 A SERD
  28. GC17803 4-Hydroxytamoxifen

    An active metabolite of tamoxifen
  29. GC15599 Hydroxyprogesterone caproate A synthetic progestogen
  30. GC11144 Chlormadinone acetate A synthetic progestin
  31. GC17475 17-Hydroxyprogesterone A steroid and precursor in the synthesis of adrenal androgens
  32. GC10012 Chlorotrianisene A synthetic non-steroidal estrogen
  33. GC11996 Ospemifene A selective estrogen receptor modulator
  34. GC14902 G-36 A selective antagonist of the estrogen receptor GPER
  35. GC16618 G-15 An antagonist of the estrogen receptor GPER
  36. GC12766 G-1

    G-1 is a selective and potent agonist of GPR30 with EC50 value about 2 nM.
  37. GC16372 (Z)-4-Hydroxytamoxifen 4-羟基他莫昔芬((Z)-4-Hydroxytamoxifen)是雌激素受体的选择性调节剂(SERM),其影响[3H]oestradiol与雌激素受体结合的IC50值为3.3 nM。
  38. GC10389 ERB 041 An ERβ agonist
  39. GC10180 Cyclofenil An Analytical Reference Standard
  40. GC12767 Zearalenone A mycotoxin
  41. GC12140 Endoxifen Endoxifen Z-异构体是最重要的他莫昔芬代谢物，负责在表达雌激素受体-α (ERα) 的乳腺癌细胞中引发该药物的抗雌激素作用。
  42. GC14131 FERb 033 FERb 033 是一种选择性有效的 ERβ 激动剂（Ki=7.1 nM，EC50=4.8 nM）。
  43. GC13309 WAY 200070 A potent and selective ERβ agonist
  44. GC10558 GSK 4716 An ERRβ/γ agonist
  45. GC10346 Y 134 Y 134 是一种选择性和口服活性的雌激素受体 (ER) 调节剂 (SERM)，对 ERα 和 ERβ 表现出有效的拮抗剂活性。 Y 134 对 ERα (Ki\u003d0.09 nM) 的选择性比对 ERβ (Ki\u003d11.31 nM) 的选择性高 121.1 倍。 Y 134 抑制雌激素刺激的 ER 阳性人乳腺癌细胞增殖。
  46. GC11863 PHTPP An estrogen ERβ receptor antagonist
  47. GC16742 ZK 164015 雌激素受体沉默拮抗剂
  48. GC11881 MPP dihydrochloride MPP dihydrochloride 是一种高度选择性的雌激素受体α (ERα) 拮抗剂。 MPP dihydrochloride 降低了 p-ERα/ERα 的比率。
  49. GC17688 Diarylpropionitrile(DPN) An estrogen receptor β agonist
  50. GC14370 PPT A selective estrogen receptor α agonist
  51. GC13373 (R)-DPN R)-DPN (compound 3) 是一种选择性 ERβ 配体，对 ERα 和 ERβ 的 EC50 分别为 2.9 和 0.8 nM。

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