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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis(其他细胞凋亡)

  1. Cat.No. 产品名称 Information
  2. GC18109 Astragaloside A A bioactive saponin from Astragalus
  3. GC13442 Sanguinarine chloride A natural alkaloid with anti-inflammatory and anti-oxidant properties
  4. GC12822 BML-210(CAY10433) A potent, synthetic HDAC inhibitor
  5. GC17901 Tamoxifen Tamoxifen(他莫西芬)是一种选择性雌激素受体调节剂 (SERM),可阻断乳腺细胞中的雌激素作用,并可激活不同组织细胞中的雌激素活性;Tamoxifen 还可以作为 Hsp90 激活剂,增强 Hsp90 分子伴侣 ATPase 的活性;Tamoxifen 还可以诱导 CreER(T2) 小鼠的基因敲除[1-4]。
  6. GC12074 BG45 A selective HDAC3 inhibitor
  7. GC12375 PF-4989216 An orally bioavailable PI3K inhibitor
  8. GC13219 ONO-4059 A derivative of ONO-4059
  9. GC14218 TP-0903 An Axl kinase inhibitor
  10. GC12387 Tiplaxtinin(PAI-039) A PAI-1 inhibitor
  11. GC13526 Spautin-1 An autophagy inhibitor
  12. GC16827 ELR510444 An inhibitor of tubulin polymerization
  13. GC14644 SBE 13 HCl A potent Plk1 inhibitor
  14. GC12222 Pexidartinib (PLX3397) A multi-targeted receptor tyrosine kinase inhibitor
  15. GC15654 SBI-0206965 An ULK1 and ULK2 inhibitor
  16. GC16310 FTI 277 HCl FTI 277 HCl 是法尼基转移酶 (FTase) 的抑制剂；一种高效的 Ras CAAX 肽模拟物，可拮抗 H-和 K-Ras 致癌信号传导。
  17. GC17916 Poziotinib An inhibitor of EGFRs
  18. GC14707 Purvalanol A A selective inhibitor of cyclin-dependent kinases
  19. GC10093 LY2409881 A selective IKK2 inhibitor
  20. GC16208 HO-3867 A selective STAT3 inhibitor
  21. GC13474 Garcinol A polyisoprenylated benzophenone with diverse biological activities
  22. GC15896 Z-Ile-Leu-aldehyde Z-Ile-Leu-aldehyde (Z-IL-CHO) 是一种有效的、竞争性的 γ-分泌酶和缺口肽醛抑制剂。
  23. GC14631 SP2509 A reversible inhibitor of LSD1
  24. GC11574 HPOB A potent and selective inhibitor of HDAC6
  25. GC12348 Ro 3306 An inhibitor of Cdk1
  26. GC10021 CPI-360 A selective EZH2 inhibitor
  27. GC11784 LCZ696 A dual angiotensin II receptor antagonist and neprilysin inhibitor
  28. GC14794 PF-06463922 An orally available inhibitor of ALK and ROS1
  29. GC12247 K-Ras(G12C) inhibitor 12 An allosteric inhibitor of oncogenic K-Ras(G12C)
  30. GC11973 HSP990 (NVP-HSP990) An Hsp90 inhibitor
  31. GC16511 OTS964 A TOPK inhibitor
  32. GC16479 UC 112 UC 112 是一种新型强效 IAP（凋亡抑制剂）抑制剂；有效抑制两种人黑色素瘤（A375 和 M14）和两种人前列腺（PC-3 和 DU145）癌细胞系的细胞生长（IC50\u003d0.7-3.4 uM）。
  33. GC11971 LY2857785 A Cdk9 inhibitor
  34. GC12178 G-749 An FLT3 kinase inhibitor
  35. GC11834 Epibrassinolide A brassinosteroid with protective effects
  36. GC11990 TCS-PIM-1-4a TCS-PIM-1-4a (SMI-4a) 是一种泛 Pim 激酶抑制剂，通过激活 AMPK 来阻断 mTORC1 的活性。 TCS-PIM-1-4a 可杀死多种髓系和淋巴系细胞系（IC50 值范围为 0.8 μM 至 40 μM）。
  37. GC10334 INH6 A Hec1/Nek2 inhibitor
  38. GC11445 YH239-EE A prodrug form of YH 239
  39. GC17067 LDC000067 A Cdk9 inhibitor
  40. GC10666 CGP 57380 Inhibitor of MAPK-interacting kinase1
  41. GC16713 HS-173 A PI3K inhibitor
  42. GC10098 (S)-10-Hydroxycamptothecin A DNA topoisomerase I inhibitor
  43. GC14853 TC ASK 10 A inhibitor of ASK1
  44. GC11985 SC 66 A dual inhibitor of Akt
  45. GC14561 SCH 529074 An activator of p53
  46. GC16597 Alda 1

    A selective ALDH2 agonist
  47. GC14233 BIO-acetoxime A potent, selective inhibitor of GSK3α/β
  48. GC16853 7,8-Dihydroxyflavone A TrkB kinase inhibitor
  49. GC11869 SZL P1-41 An inhibitor of Skp2
  50. GC15104 (R)-(+)-Etomoxir sodium salt (R)-(+)-Etomoxir sodium salt(Etomoxir) is a small molecule developed for metabolic and cardiovascular disease that exhibits nanomolar potency toward CPT-1a and CPT-1b upon enzymatic conversion to the active inhibitor etomoxiryl CoA (IC50 = 0.
  51. GC10389 ERB 041 An ERβ agonist

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