FXR & LXR
FXR (farnesoid X receptor) is a nuclear receptor that binds to hormone response elements on DNA, regulating the expression of certain genes when it is activated.
LXR (liver X receptor) is a member of the nuclear receptor family of transcription factors and is an important regulator of cholesterol, fatty acid, and glucose homeostasis.
Products for FXR & LXR
- Cat.No. 产品名称 Information
- GC32054 Rovazolac Rovazolac是从来自专利WO2013130892A1中的肝脏x受体(liverxreceptor(LXR))调节剂。
- GN10024 Saikosaponin A A triterpenoid saponin with diverse biological activities
- GC37630 Sevelamer Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
- GC11885 Sevelamer HCl Sevelamer HCl 是一种磷酸盐结合药物,用于治疗慢性肾病患者的高磷血症;由与环氧氯丙烷交联的聚烯丙胺组成。
- GC45567 SR 1903 A modulator of RORγ and LXR receptors
- GC13680 SR-9243 An LXR inverse agonist
- GC14638 SR9238 A liver-specific inverse agonist of LXR
- GC10596 T0901317 Selective agonist for LXRα and LXRβ
- GC44999 Tauro-α-muricholic Acid (sodium salt) An FXR receptor antagonist
- GC49011 Tauro-α-muricholic Acid-d4 (sodium salt) An internal standard for the quantification of tauro-α-muricholic acid
- GC45000 Tauro-β-muricholic Acid (sodium salt) An FXR receptor antagonist
- GC49012 Tauro-β-muricholic Acid-d4 (sodium salt) tauro-β-muricholic acid 定量的内标
- GC44998 Tauro-Obeticholic Acid An active metabolite of obeticholic acid
- GC19363 Tropifexor An FXR agonist
- GC32459 XL041 (BMS-852927) XL041 (BMS-852927) (BMS-852927) 是一种 LXRβ-选择性激动剂。
- GC10760 XL335 A potent and selective FXR agonist