Home>>Lipids>> Octadecanoids>>(R)-(-)-Linoleyl-2'-Hydroxy-1'-Propylamide

(R)-(-)-Linoleyl-2'-Hydroxy-1'-Propylamide

目录号 : GC91261

LOEA的同源物

(R)-(-)-Linoleyl-2'-Hydroxy-1'-Propylamide Chemical Structure

规格 价格 库存 购买数量
1 mg
¥1,139.00
现货
5 mg
¥5,033.00
现货
10 mg
¥8,926.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Linoleoyl ethanolamide (LOEA) has potential signaling roles in aging and neurological functioning.1,2 LOEA has a weak affinity for cannabinoid (CB) receptors (Ki = 10, 25 μM for CB1, CB2, respectively) and inhibits voltage-gated K+ channels.3,4 LOEA also inhibits fatty acid amide drolase (FAAH; Ki = 9 μM) and is drolyzed by FAAH.5,6 (R)-(−)-Linoleyl-2’-droxy-1’-propylamide is a homolog of LOEA which is characterized by the addition of an (R)-β-metl group at the terminal ethanolamine carbon. A similar modification of arachidonoyl ethanolamide to produce R-2 methanandamide imparts diminished affinity for the CB receptor as well as reduced metabolic stability.7 The psiological actions of this compound have not been evaluated.

Chemical Properties

Cas No. SDF
分子式 C21H39NO2 分子量 337.5
溶解度 DMF: 11 mg/ml,DMSO: 5 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 11 mg/ml 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 2.963 mL 14.8148 mL 29.6296 mL
5 mM 0.5926 mL 2.963 mL 5.9259 mL
10 mM 0.2963 mL 1.4815 mL 2.963 mL
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*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % saline
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