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Pyrene phosphoramidite dU Sale

目录号 : GC14718

Fuorescent oligoDNA probe

Pyrene phosphoramidite dU Chemical Structure

Cas No.:199920-17-7

规格 价格 库存 购买数量
100mg
¥1,071.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Pyrene is polycyclic aromatic hydrocarbon which is well-known for its ability to intercalate into DNA. Pyrene features intense blue fluorescence. Its parameters depend strongly on fluorophore microenvironment. Therefore, fluorescence spectra of pyrene are used for the extraction of structural information about site surrounding pyrene. Two pyrenes in close proximity usually form excimers easily detectable by excimer fluorescence. Pyrene can also be a FRET donor to other fluorophores such as perylene. With this phosphoramidite, pyrene can be introduced into DNA or RNA by means of automated synthesis. This pyrene phosphoramidite contains hydrocarbon moiety rigidly attached to deoxyuridine. This reagent allows to attach pyrene fragment to 5', internal, or 3' position (using universal support). This amidite requires no special handling, coupling, or deprotection conditions. Recommended diluent for it is acetonitrile. Pyrene dU amidite

Chemical Properties

Cas No. 199920-17-7 SDF
化学名 3-[[(2R,3R,5R)-5-[5-[2-(8,10b-dihydropyren-1-yl)ethynyl]-2,4-dioxopyrimidin-1-yl]-2-[bis(4-methoxyphenyl)methoxymethyl]oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Canonical SMILES CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)N4C=C(C(=O)NC4=O)C#CC5=CC=C6C=CC7=C8C6C5=CC=C8CC=C7
分子式 C57H55N4O8P 分子量 955.04
溶解度 good in dichloromethane and acetonitrile 储存条件 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.0471 mL 5.2354 mL 10.4708 mL
5 mM 0.2094 mL 1.0471 mL 2.0942 mL
10 mM 0.1047 mL 0.5235 mL 1.0471 mL
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