Home>>Signaling Pathways>> Ubiquitination/ Proteasome>> Autophagy>>(-)-PX20606 trans isomer ((-)-PX-102 trans isomer)
(-)-PX20606 trans isomer ((-)-PX-102 trans isomer) 目录号 GC31386

(-)-PX20606transisomer是一种FXR激动剂,在FRET和M1H测定中对于FXR的EC50值分别为18和29nM。

规格 价格 库存 购买数量
10mM*1mLinDMSO
¥14,979.00
现货
1mg
¥3,124.00
现货
2mg
¥4,909.00
现货

Customer Review

Based on customer reviews.

电话:400-920-5774 Email: sales@glpbio.cn

Sample solution is provided at 25 µL, 10mM.

质量管理

Quality Control & SDS

View current batch:

Chemical Properties

Cas No. 1268244-88-7 SDF Download SDF
别名 N/A
化学名 N/A
Canonical SMILES ClC1=C(C2=NOC(C3CC3)=C2COC4=CC=C([C@@H]5C[C@H]5C6=CC=C(C(O)=O)C=C6)C(Cl)=C4)C(Cl)=CC=C1.[(-)].[Rotation]
分子式 C29H22Cl3NO4 分子量 554.85
溶解度 Ethanol : ≥ 50 mg/mL (90.11 mM) 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
  • 摩尔浓度计算器

  • 稀释计算器

质量
=
浓度
x
体积
x
分子量
 
 
 
*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算

产品描述

(-)-PX20606 trans isomer is a FXR agonist with EC50s of 18 and 29 nM for FXR in FRET and M1H assay, respectively.

[1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53.