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Praziquantel Sale

(Synonyms: 吡喹酮) 目录号 : GC13197

An anthelmintic agent

Praziquantel Chemical Structure

Cas No.:55268-74-1

规格 价格 库存 购买数量
10mM (in 1mL DMSO) 待询 待询
50mg 待询 待询
5g
¥662.00
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产品描述

Praziquantel is an anthelmintic effective against flatworms.Target: AntiparasiticPraziquantel is the drug of choice for treatment of all human schistosomes. Infected mice were treated with increasing Praziquantel doses until the highest dose of 3 × 300 mg/Kg was reached. The effect of Praziquantel treatment on the parasite population was assessed using five polymorphic microsatellite markers. Parasitological and genetic data were compared with those of the untreated control. After six parasite generations submitted to treatment, it was possible to obtain a S. mansoni population with decreased susceptibility to Praziquantel. In our experiments we also observed that female worms were more susceptible to Praziquantel than male worms [1, 2].

References:
[1]. Coeli, R., et al., Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections. PLoS Negl Trop Dis, 2013. 7(12): p. e2596.
[2]. Mekonnen, A., et al., Efficacy of Praziquantel against Schistosoma haematobium in Dulshatalo village, western Ethiopia. BMC Res Notes, 2013. 6: p. 392.

Chemical Properties

Cas No. 55268-74-1 SDF
别名 吡喹酮
化学名 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
Canonical SMILES C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
分子式 C19H24N2O2 分子量 312.41
溶解度 ≥ 14.35mg/mL in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.2009 mL 16.0046 mL 32.0092 mL
5 mM 0.6402 mL 3.2009 mL 6.4018 mL
10 mM 0.3201 mL 1.6005 mL 3.2009 mL
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