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parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] Sale

(Synonyms: H2N-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH ) 目录号 : GP10014

Enhancer of blood calcium level

parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] Chemical Structure

规格 价格 库存 购买数量
1mg
¥966.00
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5mg
¥2,835.00
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10mg
¥4,484.00
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25mg
¥6,657.00
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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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产品描述

parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis], (C154H246N48O40S2),a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium (Ca2+) in the blood, PTH acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor and the parathyroid hormone 2 receptor(1). PTH reduces the reabsorption of phosphate from the proximal tubule of the kidney,[8] which means more phosphate is excreted through the urine. PTH enhances the uptake of phosphate from the intestine and bones into the blood(2). In the bone, slightly more calcium than phosphate is released from the breakdown of bone. In the intestines, absorption of both Calcium and Phosphate is mediated by an increase in activated vitamin D.

References:
1. Bieglmayer C, Prager G, Niederle B (October 2002). "Kinetic analyses of parathyroid hormone clearance as measured by three rapid immunoassays during parathyroidectomy". Clin. Chem. 48 (10): 1731-8.
2. PooleK, Reeve J (2005). "Parathyroid hormone - a bone anabolic and catabolic agent". Curr Opin Pharmacol 5 (6): 612-7.

Chemical Properties

Cas No. SDF
别名 H2N-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
分子式 C154H246N48O40S2 分子量 3474.03
溶解度 ≥ 347.4mg/mL in DMSO 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.2879 mL 1.4393 mL 2.8785 mL
5 mM 0.0576 mL 0.2879 mL 0.5757 mL
10 mM 0.0288 mL 0.1439 mL 0.2879 mL
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