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N-tridecanoyl-L-Homoserine lactone Sale

(Synonyms: C13HSL) 目录号 : GC44472

An N-acyl homoserine lactone

N-tridecanoyl-L-Homoserine lactone Chemical Structure

Cas No.:878627-21-5

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5mg
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50mg
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. N-tridecanoyl-L-Homoserine lactone (C13-HSL) possesses a rare odd-numbered acyl carbon chain and is produced by wild-type and mutant strains of Y. pseudotuberculosis in trace amounts.

Chemical Properties

Cas No. 878627-21-5 SDF
别名 C13HSL
Canonical SMILES CCCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
分子式 C17H31NO3 分子量 297.4
溶解度 DMF: 0.25 mg/ml 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.3625 mL 16.8124 mL 33.6247 mL
5 mM 0.6725 mL 3.3625 mL 6.7249 mL
10 mM 0.3362 mL 1.6812 mL 3.3625 mL
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