|MPP+ Iodide 目录号 GC18188|
Sample solution is provided at 25 µL, 10mM.
|Cas No.||36913-39-0||SDF||Download SDF|
|溶解度||100 mM in Water||储存条件||Store at-20°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
MPP+ is an active metabolite of MPTP , a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative stress. The key features of different neurotoxic models of Parkinson’s disease, including the MPTP model, have been detailed.