Home>>Infectious Disease>> Fungal Diseases>> Candidiasis>>Levorin Complex

Levorin Complex

(Synonyms: 杀念菌素) 目录号 : GC40031

An antifungal complex

Levorin Complex Chemical Structure

Cas No.:1403-17-4

规格 价格 库存
1mg
¥4,711.00
待询
5mg
¥16,498.00
待询

电话:400-920-5774 Email: sales@glpbio.cn

Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

View current batch:

产品描述

Levorin complex is a macrocyclic heptaene antifungal complex originally isolated from S. griseus. It is active against C. albicans, T. glabrata, A. niger, T. mentagrophytes, and T. soudanense in vitro (MICs = 0.03-25 μg/ml). Oral administration of levorin complex reduces mortality in a mouse model of C. albicans infection with a protective dose (PD50) value of 25 mg/kg. This product is a mixture of levorin A0, levorin A2, and levorin A3.

Chemical Properties

Cas No. 1403-17-4 SDF
别名 杀念菌素
分子式 C59H84N2O18 (for Levorin A2) 分子量 1109.3
溶解度 DMF: soluble,DMSO: soluble, heated,Ethanol: soluble,Methanol: soluble 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 0.9015 mL 4.5073 mL 9.0147 mL
5 mM 0.1803 mL 0.9015 mL 1.8029 mL
10 mM 0.0901 mL 0.4507 mL 0.9015 mL
  • 摩尔浓度计算器

  • 稀释计算器

  • 分子量计算器

质量
=
浓度
x
体积
x
分子量
 
 
 
*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % saline
计算重置

Research Update

[Characteristics of diffusion of polyene antibiotic levorin]

Antibiot Khimioter 1991 Feb;36(2):8-11.PMID:2025123doi

Studies were performed which provided estimation of the impact of some physico-chemical properties of levorin, a polyene antibiotic, and in particular its multicomponent nature and capacity for isomerization on formation of inhibition zones in assay of the antibiotic activity by the agar diffusion method. It was shown that the Levorin Complex components markedly differed in the biological activity and diffusion capacity. The diffusive properties of the highly active components A2 and A3 were better. The diffusion rate of isomerized levorin was much lower than that of the initial levorin. To provide better diffusion of the levorin components with low diffusion capacity it was recommended to use a new solution composed of ethanol, glycerol and water at a ratio of 15:25:60.