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L-Methionine-d3 Sale

(Synonyms: L-蛋氨酸-d3) 目录号 : GC49368

An internal standard for the quantification of L-methionine

L-Methionine-d3 Chemical Structure

Cas No.:13010-53-2

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100 mg
¥529.00
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500 mg
¥1,981.00
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1 g
¥3,175.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

L-Methionine-d3 is intended for use as an internal standard for the quantification of L-methionine by GC- or LC-MS. L-Methionine is an essential amino acid.1,2 It is catabolized by methionine adenosyltransferase 2A (MAT2A), yielding the universal methyl donor S-.2 L-methionine has roles in purine and pyrimidine synthesis, polyamine synthesis, and glutathione production, as well as in various metabolic diseases and aging. Dietary methionine restriction (MR) prevents accelerated aging in a mouse model of progeria and increases the lifespan of yeast, Drosophila, C. elegans, mice, and rats.1,2 MR also improves insulin sensitivity and reduces adiposity in mice, as well as inhibits the growth and proliferation of several cancer cell lines.

1.Wanders, D., Hobson, K., and Ji, X.Methionine restriction and cancer biologyNutrients12(3)684(2020) 2.Sanderson, S.M., Gao, X., Dai, Z., et al.Methionine metabolism in health and cancer: A nexus of diet and precision medicineNat. Rev. Cancer19(11)625-637(2019)

Chemical Properties

Cas No. 13010-53-2 SDF
别名 L-蛋氨酸-d3
Canonical SMILES OC([C@@H](N)CCSC([2H])([2H])[2H])=O
分子式 C5H8D3NO2S 分子量 152.2
溶解度 DMF: insol,DMSO: insol,Ethanol: insol,PBS (pH 7.2): 10 mg/ml 储存条件 -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 6.5703 mL 32.8515 mL 65.703 mL
5 mM 1.3141 mL 6.5703 mL 13.1406 mL
10 mM 0.657 mL 3.2852 mL 6.5703 mL
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