Viral Diseases(病毒性疾病)

Cat.No. 产品名称 Information

GC62750 (S)-Enzaplatovir (S)-Enzaplatovir ((S)-BTA-C585) 是 Enzaplatovir 的S-对映体。(S)-Enzaplatovir 显示出对呼吸道合胞病毒 (RSV) 的 EC50 为56 nM (专利WO2011094823A1 compound 77)。

GC49437 Gliotoxin-13C13 An internal standard for the quantification of gliotoxin

GC49400 SN-011 A STING antagonist

GC49395 Ribavirin-13C5 An internal standard for the quantification of ribavirin

GC49382 L-Lysine-d3 (hydrochloride) An internal standard for the quantification of L-lysine

GC49357 N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester A synthetic intermediate

GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine

GC49284 GSK-A1 A PI4KIIIα inhibitor

GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor

GC49228 Ganoderol B A triterpenoid with diverse biological activities

GC49177 Loliolide A monoterpene lactone with diverse biological activities

GC49167 (R)-(+)-Trityl glycidyl ether A synthetic precursor

GC49165 GS-441524 tris-isobutyryl ester An orally bioavailable prodrug form of GS-443902

GC49153 Didemnin B A depsipeptide with diverse biological activities

GC49148 Plitidepsin A depsipeptide with diverse biological activities

GC49122 3′-deoxy Thymidine An antiviral nucleoside analog

GC49077 Podophyllotoxin-d6 An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin

GC49057 Azelastine-13C-d3 (hydrochloride) An internal standard for the quantification of azelastine

GC49010 Taurohyocholic Acid-d4 (sodium salt) An internal standard for the quantification of taurohyocholic acid

GC48969 Withanone A phytochemical with diverse biological activities

GC62720 Lactimidomycin Lactimidomycin 是从链霉菌中分离出的含戊二酰亚胺的化合物。Lactimidomycin 是一种有效的真核翻译延伸抑制剂，对肿瘤细胞系具有有效的抗增殖作用，并选择性抑制蛋白质翻译。Lactimidomycin 抑制蛋白质合成，IC50 值为 37.82 nM。Lactimidomycin 还是登革热病毒 2 和其他 RNA 病毒的有效且无毒的抑制剂。抗癌和抗病毒活性。

GC62625 Pritelivir mesylate Pritelivir mesylate (BAY 57-1293 mesylate) 是一种病毒解旋酶-引物酶复合物 (helicase-primase complex) 抑制剂，在体外和单纯疱疹病毒 (HSV) 感染的动物模型中均具有抗病毒活性。Pritelivir mesylate 对 1 型和 2 型单纯疱疹病毒 (HSV-1 和 HSV-2) 具有活性，对 HSV1-2 的 IC50 为 0.02 μM。

GC62610 Aplaviroc hydrochloride Aplaviroc (AK 602) hydrochloride，SDP的一个衍生物，是 CCR5 的拮抗剂，其对 HIV-1Ba-L， HIV-1JRFL 和 HIV-1MOKW 的 IC50 值为 0.1-0.4 nM。

GC62607 EFdA-TP tetraammonium EFdA-TP tetraammonium 是一种有效的核苷逆转录酶 (RT) 抑制剂。EFdA-TP tetraammonium 作为有效的立即或延迟链终止剂 (ICT 或 DCT) 抑制 RT 催化的 DNA 合成。EFdA-TP tetraammonium 通过多种机制抑制 HIV-1 RT。

GC62295 Elsulfavirine Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection.

GC62251 Laninamivir octanoate Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.

GC62244 Oseltamivir-acetate Oseltamivir-acetate 是 Oseltamivir 的杂质。Oseltamivir 是一种神经氨酸酶 (neuraminidase) 抑制剂，用于流感 (influenza A 和 B) 的研究。

GC62217 Sisunatovir hydrochloride Sisunatovir (RV521) hydrochloride 是一种口服 RSV 融合 (RSV-F) 蛋白抑制剂，对一组临床分离的 RSV-A 和 RSV-B 病毒具有很强的疗效，对 RSV-A 和 RSV-B 分离株的 IC50 分别为 1.4 nM 和 1.0 nM。

GC62216 Sisunatovir Sisunatovir (RV521) 是一种口服 RSV 融合 (RSV-F) 蛋白抑制剂，对一组临床分离的 RSV-A 和 RSV-B 病毒具有很强的疗效，对 RSV-A 和 RSV-B 分离株的 IC50 分别为 1.4 nM 和 1.0 nM。

GC62210 ONX-0914 TFA A selective inhibitor of the β5i (LMP7) subunit of the immunoproteasome

GC62162 Molnupiravir A prodrug form of EIDD-1931

GC62116 CBS1117 CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1), also interferes with the hemagglutinin (HA)-mediated fusion process.