Home>>Histone H3K27Me3 (21-44)-K-biotin (trifluoroacetate salt)

Histone H3K27Me3 (21-44)-K-biotin (trifluoroacetate salt)

目录号 : GC43850

Histone H3K27Me3 (21-44)-K-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences.

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250μg
¥2,253.00
现货
1mg
¥6,759.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Histone H3K27Me3 (21-44)-K-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and H3.2 sequences. It is trimethylated at lysine 27 and biotinylated via a C-terminal lysine linker. Trimethylation of histone H3 at lysine 27 is associated with gene silencing. It is involved in tumor progression through its regulation by enhancer of zeste homolog 2 (EZH2) and transcriptional repression of tumor suppressor genes. Levels of H3K27Me3 are reduced in 293 T-REx cells containing EEDR236T and SUZ12G610V mutations and in lymphoblastoid cells isolated from patients with Weaver syndrome, a rare overgrowth disorder characterized by EZH2, EED, or SUZ12 mutations, cancer susceptibility, and various distinctive physical features.

Chemical Properties

Cas No. N/A SDF
别名 N/A
化学名 N/A
Canonical SMILES N/A
分子式 C128H217N43O32S•XCF3COOH 分子量 2902.4
溶解度 Water: 1 mg/ml 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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