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HCV Core 22kDa

目录号 : GP25249

Hepatitis C Virus Core 22kDa Recombinant

HCV Core 22kDa Chemical Structure

规格 价格 库存 购买数量
100μg
¥2,310.00
5-10工作日
500μg
¥9,240.00
5-10工作日
1mg
¥18,900.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

The E.coli derived recombinant protein contains the HCV core nucleocapsid genotype 1b, immunodominant regions, amino acids 2-192, 22kDa.The protein is fused with b-galactosidase (114 kDa) at N-terminus.

Product Data

Purity HCV-Core Protein is >95% pure as determined by 10% PAGE (coomassie staining). Source
Phycical Appearance Shipping Condition Shipped with Ice Packs.
Amino Acid Sequence mstnpkpqrk tkrntnrrpq dvkfpgvgqi vggvyllprr gprlgvratr ktsersqprg rrqpipkarr pegrtwaqpg ypwplygneg cgwagwllsp rgsrpswgpt dprrrsrnlg kvidtltcgf adlmgyiplv gaplggaara lahgvrvled gvnyatgnlp gcsfsiflla llscltvpa
Stability HCV-Corealthough stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.
Formulation 20mM Tris HCl pH-8, 8M urea and 10mM b-mercaptoethanol.

Introduction

HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Purification Method

HCV-Core protein was purified by proprietary chromatographic technique.

Stability

HCV-Corealthough stable at 4°C for 1 week, should be stored below -18°C .Please prevent freeze thaw cycles.