GZMH Human
目录号 : GP21767Granzyme-H Human Recombinant
Sample solution is provided at 25 µL, 10mM.
Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
Synonyms | Granzyme H (Cathepsin G-Like 2; Protein H-CCPX); CTSGL2; Cytotoxic T-Lymphocyte Proteinase; CCP-X; CSP-C; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Cytotoxin Serine Protease-C; Cytotoxic Serine Protease C; Cathepsin G-Like 2; EC 3.4.21.79; EC 3.4.21; Granzyme H; EC 3.4.21; CGL-2; CTLA1; CGL2; GZMH. | ||
Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGS SINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKP GQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVC KDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRL | ||
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
Formulation | GZMH protein solution (0.25mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol. |
Granzyme H also known as GZMH belongs to the peptidase S1 family. GZMHis an essential part for HBV eradication. The HBx protein, which is requiredfor the replication of HBV, is cleaved at Met(79) by GZMH. Furthermore, GZMHinhibitor can abolish GZNH- as well as lymphokine-activated killercell-mediated HBx degradation and HBV clearance. A HBx-deficient HBV isresistant to GzmH- in addition to lymphokine-activated killer cell-mediatedviral clearance.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.