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GZMH Human, sf9

目录号 : GP21768

Granzyme-H Human Recombinant, sf9

GZMH Human, sf9 Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
100μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

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产品描述

GZMH produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 234 amino acids (19-246 a.a.) and having a molecular mass of 26.2kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). GZMH is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 90.0% as determined by SDS-PAGE. Source Sf9, Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms Granzyme H; Granzyme H (Cathepsin G-Like 2; ProteinH-CCPX); Cytotoxic T-Lymphocyte Proteinase; Cathepsin G-Like 2; CTSGL2; CCP-X;CSP-C; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Cathepsin G-Like 2;Protein H-CCPX; Cytotoxin Serine Protease-C; Cytotoxic Serine Protease C;Protein H-CCPX; EC 3.4.21.79; EC 3.4.21; EC 3.4.21; CTLA1; CGL-2 ; CGL2.
Amino Acid Sequence EEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGSSINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKPGQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVCKDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRLHH HHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation GZMH protein solution (0.25mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Introduction

Granzyme H also known as GZMH belongs to the peptidase S1 family. GZMH is an essential part for HBV eradication. The HBx protein, which is required for the replication of HBV, is cleaved at Met(79) by GZMH. Furthermore, GZMH inhibitor can abolish GZNH- as well as lymphokine-activated killer cell-mediated HBx degradation and HBV clearance. A HBx-deficient HBV is resistant to GzmH- in addition to lymphokine-activated killer cell-mediated viral clearance.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.