Perfluoro-n-pentane
(Synonyms: 全氟正戊烷) 目录号 : GD20346Perfluoro-n-pentane是一种全氟化合物，具有出色的化学稳定性和耐高温性。
Cas No.:678-26-2
Sample solution is provided at 25 µL, 10mM.
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Perfluoro-n-pentane is a perfluorinated compound and has excellent chemical stability and high temperature resistance[1]. Perfluoro-n-pentane is widely used in the medical field, especially as an ultrasound contrast agent[2][3]. Perfluoro-n-pentane has high potential in research of drug delivery, acts as a carrier for drug sustained-release systems, improving drug efficacy and reducing side effects[4][5]. In the industrial area, Perfluoro-n-pentane can be used as an insulating material or for fire suppression systems to effectively protect equipment and buildings from fire and high temperatures[6].
References:
[1]. Stiles V E, Cady G H. Physical Properties of Perfluoro-n-hexane and Perfluoro-2-methylpentane[J]. Journal of the American Chemical Society, 1952, 74(15): 3771-3773.
[2]. Yang Q, Chen H, Bai Y, et al. Facile Synthesis of Lipid-Perfluorocarbon Nanoemulsion Coated with Silica Shell as an Ultrasound Imaging Agent. Adv Healthc Mater. 2018 Feb;7(4). doi: 10.1002/adhm.201700816. Epub 2017 Dec 21. PMID: 29266872.
[3]. Ferri S, Wu Q, De Grazia A, et al. Tailoring the size of ultrasound responsive lipid-shelled nanodroplets by varying production parameters and environmental conditions. Ultrason Sonochem. 2021 May;73:105482. doi: 10.1016/j.ultsonch.2021.105482. Epub 2021 Feb 3. PMID: 33588208; PMCID: PMC7901031.
[4]. Wilson MG, Parikh A, Dara A, et al. Targeted drug release from stable and safe ultrasound-sensitive nanocarriers. Front Mol Biosci. 2024 Jun 19;11:1408767. doi: 10.3389/fmolb.2024.1408767. PMID: 38962281; PMCID: PMC11219560.
[5]. Du M, Wang T, Feng R, et al. Establishment of ultrasound-responsive SonoBacteriaBot for targeted drug delivery and controlled release. Front Bioeng Biotechnol. 2023 Feb 24;11:1144963. doi: 10.3389/fbioe.2023.1144963. PMID: 36911192; PMCID: PMC9998949.
[6]. Liu H, Zhang T, Zhang M, et al. Preparation and thermal responsiveness of microencapsulated fluorinated liquids for automatic fire extinguishing. Heliyon. 2024 Mar 3;10(5):e27454. doi: 10.1016/j.heliyon.2024.e27454. PMID: 38463842; PMCID: PMC10924043.
Perfluoro-n-pentane是一种全氟化合物，具有出色的化学稳定性和耐高温性[1]。Perfluoro-n-pentane在医学领域被广泛应用，尤其是作为超声造影剂[2][3]。Perfluoro-n-pentane在药物递送研究中有巨大潜力，可作为药物缓释系统的载体，提高药物疗效并减少副作用[4][5]。在工业领域，Perfluoro-n-pentane可用作绝缘材料或灭火系统，有效保护设备和建筑物免受火灾和高温的影响[6]。
| Cas No. | 678-26-2 | SDF | |
| 别名 | 全氟正戊烷 | ||
| 分子式 | C5F12 | 分子量 | 288.03 |
| 溶解度 | 储存条件 | 2-8°C | |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 3.4719 mL | 17.3593 mL | 34.7186 mL |
| 5 mM | 0.6944 mL | 3.4719 mL | 6.9437 mL |
| 10 mM | 0.3472 mL | 1.7359 mL | 3.4719 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
-
Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet