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GATC Human

目录号 : GP21661

Glutamyl-TRNA Amidotransferase, Subunit C Human Recombinant

GATC Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
100μg
¥16,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

GATC Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 159 amino acids (1-136 a.a) and having a molecular mass of 17.5kDa (Molecular size on SDS-PAGE will appear higher).

Product Data

Purity Greater than 85.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Glutamyl-TRNA(Gln) Amidotransferase Subunit C; Glu-AdTSubunit C; 15E1.2; Glutamyl-TRNA(Gln) Amidotransferase Subunit C Homolog(Bacterial); Glutamyl-TRNA(Gln) Amidotransferase Subunit C Mitochondrial; Glutamyl-TRNA(Gln)Amidotransferase Subunit C Homolog; EC 6.3.5; Protein 15E1.2.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMWSRLVW LGLRAPLGGR QGFTSKADPQ GSGRITAAVI EHLERLALVDFGSREAVARL EKAIAFADRL RAVDTDGVEP MESVLEDRCL YLRSDNVVEG NCADELLQNS HRVVEEYFVAPPGNISLPKL DEQEPFPHS
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation GATC protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.

Introduction

Glutamyl-TRNAAmidotransferase, Subunit C also known as GATC allows the formation of properlycharged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) inthe mitochondria. The reaction occurs in the attendance of glutamine and ATP throughan activated gamma-phospho-Glu-tRNA(Gln). In addition, GATC is subunit of theheterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (PET112)and C (GATC) subunits.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.