Gallic Acid-d2
(Synonyms: 3,4,5-Trihydroxybenzoic Acid-d2) 目录号 : GC49420
An internal standard for the quantification of gallic acid
Cas No.:294660-92-7
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Gallic acid-d2 is intended for use as an internal standard for the quantification of gallic acid by GC- or LC-MS. Gallic acid is a phenol that has been found in C. sinensis and has diverse biological activities.1,2,3,4 It scavenges DPPH and hydroxyl radicals in cell-free assays (IC50s = 9.4 and 191 µM, respectively).1 Gallic acid (1-100 µM) reverses abscisic acid-induced inhibition of hypocotyl growth in A. caudatus seedlings.2 In vivo, gallic acid (21.8 g/kg) inhibits morpholine- and sodium nitrite-induced adenocarcinoma formation in mice.3 It also inhibits passive cutaneous anaphylaxis in mice when administered at a dose of 50 mg/kg.4
1.Cos, P., Hermans, N., Calomme, M., et al.Comparative study of eight well-known polyphenolic antioxidantsJ. Pharm. Pharmacol.55(9)1291-1297(2003) 2.Ray, S.D., Guruprasad, K.N., and Laloraya, M.M.Antagonistic action of phenolic compounds on abscisic acid-induced inhibition of hypocotyl growthJ. Exp. Bot.31(125)1651-1656(1980) 3.Mirvish, S.S., Cardesa, A., Wallcave, L., et al.Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: Effect of ascorbate, gallic acid, thiocyanate, and caffeineJ. Natl. Cancer Inst.55(3)633-636(1975) 4.Kar, K., Mohanta, P.K., Popli, S.P., et al.Inhibition of passive cutaneous anaphylaxis by compounds of Camellia sinensisPlanta Med.42(1)75-78(1981)
| Cas No. | 294660-92-7 | SDF | |
| 别名 | 3,4,5-Trihydroxybenzoic Acid-d2 | ||
| Canonical SMILES | OC(C([2H])=C1C(O)=O)=C(C(O)=C1[2H])O | ||
| 分子式 | C7H4D2O5 | 分子量 | 172.1 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 5 mg/ml | 储存条件 | -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 5.8106 mL | 29.0529 mL | 58.1058 mL |
| 5 mM | 1.1621 mL | 5.8106 mL | 11.6212 mL |
| 10 mM | 0.5811 mL | 2.9053 mL | 5.8106 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。