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Forphenicinol Sale

(Synonyms: Forfenimex) 目录号 : GC52014

An immunomodulator and a derivative of forphenicine

Forphenicinol Chemical Structure

Cas No.:71522-58-2

规格 价格 库存 购买数量
500 µg
¥4,743.00
现货
1 mg
¥8,534.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

Forphenicinol is an immunomodulator and a derivative of the bacterial metabolite forphenicine .1 It increases the phagocytosis of yeast by peritoneal macrophages isolated from thioglycolate-stimulated mice. Forphenicinol (100 µg/animal) prevents cyclophosphamide-induced suppression of delayed-type hypersensitivity (DTH), as well as enhances DTH in response to the hapten oxazolone or sheep red blood cells in mice. It enhances the bactericidal activity of macrophages against P. aeruginosa in mice when administered at a dose of 0.5 mg/kg.2 Forphenicinol (15.6-1,000 µg/animal) increases survival in a mouse model of P. aeruginosa infection.3 It also inhibits tumor growth in S180 sarcoma and IMC carcinoma mouse xenograft models when administered at doses ranging from 0.05 to 5 mg/kg per day.

1.Ishizuka, M., Ishizeki, S., Masuda, T., et al.Studies on effects of forphenicinol on immune responsesJ. Antibiot. (Tokyo)35(8)1042-1048(1982) 2.Naito, K., Arakawa, H., Watanabe, Y., et al.Protective effect of forphenicinol, a low molecular weight immunomodifier, against infection with Pseudomonas aeruginosa in mice and its mechanismsJ. Antibiot. (Tokyo)40(4)547-545(1987) 3.Ishizuka, M., Masuda, T., Kanbayashi, N., et al.Antitumor effect of forphenicinol, a low molecular weight immunomodifier, on murine transplantable tumors and microbial infectionsJ. Antibiot. (Tokyo)35(8)1049-1054(1982)

Chemical Properties

Cas No. 71522-58-2 SDF Download SDF
别名 Forfenimex
Canonical SMILES OC([C@H](C1=CC(O)=C(C=C1)CO)N)=O
分子式 C9H11NO4 分子量 197.2
溶解度 DMSO: soluble,Methanol: soluble,Water: soluble 储存条件 -20°C
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1 mg 5 mg 10 mg
1 mM 5.071 mL 25.355 mL 50.7099 mL
5 mM 1.0142 mL 5.071 mL 10.142 mL
10 mM 0.5071 mL 2.5355 mL 5.071 mL
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