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FHL3 Human

目录号 : GP23498

Four And A Half LIM Domains 3 Human Recombinant

FHL3 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

FHL3 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 303 amino acids (1-280 a.a) andhaving a molecular mass of 33.6kDa.FHL3 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 90.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Four And A Half LIM Domains 3; SLIM2; Skeletal MuscleLIM-Protein 2; FHL-3; SLIM-2; Four And A Half LIM Domains Protein 3; LIM-OnlyProtein FHL3.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMSESFDC AKCNESLYGR KYIQTDSGPY CVPCYDNTFA NTCAECQQLI GHDSRELFYE DRHFHEGCFR CCRCQRSLAD EPFTCQDSEL LCNDCYCSAF SSQCSACGET VMPGSRKLEY GGQTWHEHCF LCSGCEQPLG SRSFVPDKGA HYCVPCYENK FAPRCARCSK TLTQGGVTYR DQPWHRECLV CTGCQTPLAG QQFTSRDEDP YCVACFGELF APKCSSCKRP IVGLGGGKYV SFEDRHWHHN CFSCARCSTS LVGQGFVPDG DQVLCQGCSQ AGP.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Formulation FHL3 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

Introduction

Fourand a half LIM domains 3 (FHL3) belongs to a family of proteins containing afour-and-a-half LIM domain, which is a highly conserved double zinc fingermotif. FHL3 has been shown to interact with the cancer developmental regulatorsSMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and thehigh-affinity IgE beta chain regulator MZF-1. FHL3 is involved in tumorsuppression, repression of MyoD expression, and repression of IgE receptorexpression. Two transcript variants encoding different isoforms have been foundfor this gene.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.