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FHL2 Human

目录号 : GP23497

Four And A Half LIM Domains 2 Human Recombinant

FHL2 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
25μg
¥2,030.00
5-10工作日
1mg
¥50,400.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

FHL2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (1-279 a.a) and having a molecular mass of 34.6kDa. FHL2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Data

Purity Greaterthan 90.0% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms AAG11; DRAL; FHL-2; SLIM-3; SLIM3; Four and a half LIMdomains protein 2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; FHL2; RNA Binding Motif Protein 18; RNA-Binding Motif Protein 18; RBM18.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMTERFDC HHCNESLFGK KYILREESPY CVVCFETLFA NTCEECGKPIGCDCKDLSYK DRHWHEACFH CSQCRNSLVD KPFAAKEDQL LCTDCYSNEY SSKCQECKKT IMPGTRKMEYKGSSWHETCF ICHRCQQPIG TKSFIPKDNQ NFCVPCYEKQ HAMQCVQCKK PITTGGVTYR EQPWHKECFV CTACRKQLSG QRFTARDDFAYCLNCFCDLY AKKCAGCTNP ISGLGGTKYI SFEERQWHND CFNCKKCSLS LVGRGFLTER DDILCPDCGK DI.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation FHL2 protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0) and 10% glycerol.

Introduction

Four And A Half LIM Domains 2 (FHL2)belongs to the four-and-a-half-LIM-only protein family. Family members arecomprised of 2 highly conserved, tandemly arranged, zinc finger domains with 4highly conserved cysteines binding a zinc atom in each zinc finger. The FHL2protein is assumed to play a part in the assembly of extracellular membranes.Furthermore, FHL2 is down-regulated during transformation of normal myoblaststo rhabdomyosarcoma cells and the FHL2 functions as a link between presenilin-2and an intracellular signaling pathway.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.