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Faropenem (sodium salt hydrate) Sale

(Synonyms: 法罗培南钠2.5水合物) 目录号 : GC49287

A penem antibiotic

Faropenem (sodium salt hydrate) Chemical Structure

Cas No.:158365-51-6

规格 价格 库存 购买数量
5 mg
¥1,113.00
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10 mg
¥2,125.00
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25 mg
¥5,019.00
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50 mg
¥8,361.00
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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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产品描述

Faropenem is a broad-spectrum penem antibiotic.1 It is active against a panel of 12 Gram-positive (MIC50s = 0.008-1 mg/L) and 15 Gram-negative (MIC50s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model of H. influenzae-induced respiratory tract infection.2 Formulations containing faropenem have been used in the treatment of various bacterial infections.

1.Schurek, K.N., Wiebe, R., Karlowsky, J.a., et al.Faropenem: Review of a new oral penemExpert Rev. Anti. Infect. Ther.5(2)185-198(2007) 2.Miyazaki, S., Hosoyama, T., Furuya, N., et al.In vitro and in vivo antibacterial activities of L-084, a novel oral carbapenem, against causative organisms of respiratory tract infectionsAntimicrob. Agents Chemother.45(1)203-207(2001)

Chemical Properties

Cas No. 158365-51-6 SDF
别名 法罗培南钠2.5水合物
Canonical SMILES [O-]C(C1=C([C@]2([H])OCCC2)S[C@@]([C@@]3([H])[C@H](O)C)([H])N1C3=O)=O.[O-]C(C4=C([C@]5([H])OCCC5)S[C@@]([C@@]6([H])[C@H](O)C)([H])N4C6=O)=O.[Na+].O.O.O.O.O.[Na+]
分子式 C12H14NO5S·Na [2.5H2O] 分子量 352.3
溶解度 DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml 储存条件 -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.8385 mL 14.1924 mL 28.3849 mL
5 mM 0.5677 mL 2.8385 mL 5.677 mL
10 mM 0.2838 mL 1.4192 mL 2.8385 mL
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Research Update

Gateways to clinical trials

Methods Find Exp Clin Pharmacol 2008 Oct;30(8):643-72.PMID:19088949doi

Gateways to clinical trials is a guide to the most recent trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity(R), the drug discovery and development portal, http://integrity.prous.com. This issue focuses on the following selection of drugs: (+)-Dapoxetine hydrochloride, (S)-Tenatoprazole sodium salt monohydrate 19-28z, Acotiamide hydrochloride hydrate, ADV-TK, AE-37, Aflibercept, Albinterferon alfa-2b, Aliskiren fumarate, Asenapine maleate, Axitinib; Bavituximab, Becatecarin, beta-1,3/1,6-Glucan, Bevacizumab, Bremelanotide; Calcipotriol/betamethasone dipropionate, Casopitant mesylate, Catumaxomab, CDX-110, Cediranib, CMD-193, Cositecan; Darinaparsin, Denosumab, DP-b99, Duloxetine hydrochloride; E75, Ecogramostim, Elacytarabine, EMD-273063, EndoTAG-1, Enzastaurin hydrochloride, Eplerenone, Eribulin mesilate, Esomeprazole magnesium, Etravirine, Everolimus, Ezetimibe; Faropenem daloxate, Febuxostat, Fenretinide; Ghrelin (human); I-131 ch-TNT-1/B, I-131-3F8, Iclaprim, Iguratimod, Iloperidone, Imatinib mesylate, Inalimarev/Falimarev, Indacaterol, Ipilimumab, Iratumumab, Ispinesib mesylate, Ixabepilone; Lapatinib ditosylate, Laquinimod sodium, Larotaxel dehydrate, Linezolid, LOR-2040; Mapatumumab, MKC-1, Motesanib diphosphate, Mycophenolic acid sodium salt; NK-012; Olanzapine pamoate, Oncolytic HSV, Ortataxel; Paclitaxel nanoparticles, Paclitaxel poliglumex, Paliperidone palmitate, Panitumumab, Patupilone, PCV-9, Pegfilgrastim, Peginterferon alfa-2a, Peginterferon alfa-2b, Pertuzumab, Picoplatin, Pimavanserin tartrate, Pimecrolimus, Plerixafor hydrochloride, PM-02734, Poly I:CLC, PR1, Prasugrel, Pregabalin, Progesterone caproate, Prucalopride, Pumosetrag hydrochloride; RAV-12, RB-006, RB-007, Recombinant human erythropoietin alfa, Rimonabant, Romidepsin; SAR-109659, Satraplatin, Sodium butyrate; Tadalafil, Talampanel, Tanespimycin, Tarenflurbil, Tariquidar, Taurine, Tecovirimat, Telatinib, Telavancin hydrochloride, Telcagepant, Terameprocol, Tesofensine, Tetrodotoxin, Tezampanel, Tipifarnib, TPI-287, Tremelimumab; Valspodar, Vatalanib succinate, VCL-CB01, vCP1452, Vorinostat; XL-228; Ziprasidone hydrochloride.