Ethoprop
(Synonyms: 灭线磷) 目录号 : GC46142
An organothiophosphate nematicide and insecticide
Cas No.:13194-48-4
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >80.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Ethoprop is an organothiophosphate nematicide and insecticide.1,2,3 It decreases the infectivity of M. chitwoodi and M. hapla second-stage juveniles (EC50s = 5.6 and 6.8 μg/ml, respectively) and inhibits hatching of M. chitwoodi egg masses and M. chitwoodi and M. hapla free eggs (EC50s = 0.2, 46, and 83.3 μg/ml, respectively).2 Ethoprop (1.8 μg/g) decreases the number of M. chitwoodi nematodes in tomato roots when added to soil from fields without previous ethoprop exposure, but is biodegraded in soil from fields previously exposed to ethoprop. In field trials, it decreases the percentage of potato tubers damaged by wireworms when applied as granules in the planting furrow at a concentration of 3 kg AI/ha.3 Ethoprop is toxic to rats via oral administration and dermal contact (LD50s = 47 and 226 mg/kg, respectively) as well as inhalation (LD50 = 0.123 mg/L).1 It is also toxic to bluegill (LC50 = 0.32 mg/L). Formulations containing ethoprop have been used in the agricultural control of pests.
|2. Mojtahedi, H., Santo, G.S., and Pinkerton, J.N. Efficacy of ethoprop on Meloidogyne hapla and M. chitwoodi and enhanced biodegradation in soil. J. Nematol. 23(4), 372-379 (1991).|3. Stewart, K.M. Chemical control of wireworms (Elateridae) in potatoes. N. Z. J. Exp. Agr. 9(3-4), 357-362 (1981).|1. Authority, E.F.S. Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos. EFSA Scientific Report 66, 1-72 (2006).
| Cas No. | 13194-48-4 | SDF | |
| 别名 | 灭线磷 | ||
| Canonical SMILES | CCCSP(SCCC)(OCC)=O | ||
| 分子式 | C8H19O2PS2 | 分子量 | 242.3 |
| 溶解度 | DMF: 5mg/mL,DMSO: 5mg/mL,Ethanol: 1.6mg/mL | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 4.1271 mL | 20.6356 mL | 41.2712 mL |
| 5 mM | 0.8254 mL | 4.1271 mL | 8.2542 mL |
| 10 mM | 0.4127 mL | 2.0636 mL | 4.1271 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Efficacy of Ethoprop on Meloidogyne hapla and M. chitwoodi and Enhanced Biodegradation in Soil
J Nematol 1991 Oct;23(4):372-9.PMID:19283141doi
Responses of egg masses, free eggs, and second-stage juveniles (J2) ofMeloidogyne hapla and M. chitwoodi to Ethoprop were evaluated. The results indicated that J2 were the most sensitive, followed by free eggs and egg masses. In general, M. chitwoodi was more susceptible to Ethoprop than M. hapla. Ethoprop at 7.2 mug a.i./g soil protected tomato roots from upward migrating M. chitwoodi for 5 weeks. The zone of protection was extended to 10 and 20 cm below the root zone when 3.6 and 7.2 cm water were applied over 8 days. Ethoprop at 1.8, 3.6, and 7.2 mug a.i./g soil degraded faster and killed fewer M. chitwoodi J2 in potato field soil previously exposed to Ethoprop than in unexposed soil or sterilized exposed soil. The enhanced biodegradation property of the exposed soil lasted 17 months after the last application of Ethoprop. The limited downward movement of Ethoprop in the soil, migration of M. chitwoodi J2 into the treated zone, presence of resistant life stage(s) at the time of application, and loss of efficacy due to enhanced biodegradation may have a significant effect on the performance of Ethoprop.
Effects of Incorporation Method of Ethoprop and Addition of Aldicarb on Potato Tuber Infection by Meloidogyne hapla
J Nematol 1991 Oct;23(4S):686-92.PMID:19283186doi
The efficacy of controlling Meloidogyne hapla on potato with water incorporation of Ethoprop was compared to physical incorporation before planting. The standard practice of aldicarb application for insect control was also evaluated for M. hapla suppression with and without Ethoprop. Physical incorporation before planting by rototilling or discing reduced (P Ethoprop was not as effective as physical incorporation of Ethoprop or postplant water incorporation of aldicarb and did not reduce (P Ethoprop did not affect yield, whereas aldicarb increased yield in one experiment.
Factors affecting degradation of aldicarb and Ethoprop
J Nematol 1998 Mar;30(1):45-55.PMID:19274198doi
Chemical and microbial degradation of the nematicides-insecticides aldicarb and Ethoprop has been studied extensively in both laboratory and field studies. These studies show that temperature is the most important variable affecting the degradation rate of aldicarb and its carbamate metabolites in surface soils. Temperature and organic matter appear to be the most important variables affecting degradation rates of Ethoprop in soils under normal agricultural conditions, with organic matter being inversely related to degradation, presumably due to increased binding to soil particles. Soil moisture may be important under some conditions for both compounds, with degradation reduced in low-moisture soils. The rate of degradation of aldicarb residues (aldicarb + aldicarb sulfoxide + aldicarb sulfone) does not seem to be significantly affected by depth from soil surface, except that aldicarb residues degrade more slowly in acidic, coarse sand subsoils. Degradation of Ethoprop also continues in subsurface soils, although field data are limited due to its lower mobility. Both compounds degrade in groundwater. Because microbial activity decreases with depth below soil surface, chemical processes are important components of the degradation of both aldicarb residues and Ethoprop. For aldicarb, transformation to carbamate oxides in surface soils is primarily microbial, while degradation to noncarbamate compounds appears to be primarily the result of soil-catalyzed hydrolysis throughout the soil profile. For Ethoprop, both chemical and microbial catalyzed hydrolysis are important in surface soils, with chemical hydrolysis becoming more important with increasing depth.
Evaluation of Ethoprop and tetrathiocarbonate for reniform nematode control in pineapple
J Nematol 1995 Dec;27(4S):639-44.PMID:19277334doi
Ethoprop and disodium tetrathiocarbonate (TTC) were evaluated as replacements of fenamiphos and 1,3-dichloropropene (1,3-D) for control of Rotylenchulus reniformis on pineapple in Hawaii. Treatments were established in a field on the Del Monte Fresh Fruit (Hawaii) plantation in spring 1991. Preplant soil treatments consisted of fumigation with 1,3-D at 226 kg a.i./ha and TTC at 135 kg or 270 kg a.i./ha. Postplant nematicides for the 1,3-D treated plots were fenamiphos (3.4 kg a.i./ha trimonthly) and Ethoprop (3.4 or 6.7 kg a.i./ha monthly). Tetrathiocarbonate was applied postplant to the TTC-treated plots every 2 months at 67 kg a.i./ha. Nematode population densities were monitored in all plots at 3-month intervals. Tetrathiocarbonate was not effective in reducing the preplant soil population densities of R. reniformis or limiting subsequent nematode damage to the plants. Ethoprop and fenamiphos reduced nematode damage, resulting in greater yield in the first and second crop harvests (P < 0.05). Ethoprop was an effective alternative to fenamiphos for control of R. reniformis in pineapple.
Effect of Aldicarb, Ethoprop, and Carbofuran on Control of Coffee Root-knot Nematode, Meloidogyne exigua
J Nematol 1983 Oct;15(4):510-4.PMID:19295839doi
Egg hatch of Meloidogyne exigua was significantly inhibited in 14 days pretreatment with aldicarb, Ethoprop, or carbofnran at concentrations higher than 0.1 mug/ml; these eggs were found to delay hatch in 19 days posttreatment in Ethoprop. Aldicarb and carbofuran solutions at concentrations greater than 0.1 mug/ml significantly decreased the motility and the life span of the second-stage juveniles; aldicarb was more toxic than carbofuran to the nematode. In a field test, aldicarb (Temik 10G), Ethoprop (Mocap 10G), and carbofuran (Furadan 5G and Furadan Liquid 350F) significantly decreased M. exigua populations.