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Epoxy Fluor 7

目录号 : GC43621

A sensitive fluorescent substrate for soluble epoxide hydrolase

Epoxy Fluor 7 Chemical Structure

规格 价格 库存 购买数量
1mg
¥598.00
现货
5mg
¥2,694.00
现货
10mg
¥4,791.00
现货
50mg
¥20,956.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Soluble epoxide hydrolase (sEH) catalyzes the conversion of epoxyeicosatrienoic acids (EpETrEs) to the corresponding DiHETrEs thereby diminishing their vasodilator activity. Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation. Epoxy fluor 7 is a sensitive fluorescent substrate for soluble epoxide hydrolase (sEH) that can be used to monitor the activity of both human and mouse enzymes. Hydrolysis of the substrate epoxide yields a highly fluorescent product that can be monitored at excitation and emission wavelengths of 330 and 465 nm, respectively. Epoxy fluor 7 is more stable in aqueous solution and offers about 2-fold better sensitivity than previously used colorimetric substrates such as NEPC.

Chemical Properties

Cas No. 863223-43-2 SDF
Canonical SMILES COc1ccc2cc(ccc2c1)C(CN)OC(=O)OCC1OC1c1ccccc1
分子式 C23H19NO5 分子量 389.4
溶解度 DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml 储存条件 Store at -20°C,protect from light
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
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第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
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