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EPHB2 Human

目录号 : GP23408

EPH Receptor B2 Human Recombinant

EPHB2 Human Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

EPHB2 Human Recombinant produced in Sf9 Baculovirus cellsis a single, glycosylated polypeptide chain containing 533 amino acids (19-543a.a)and having a molecular mass of 59.1kDa (Molecular size on SDS-PAGE will appearat approximately 50-70kDa). EPHB2 is fused to a 8 amino acid His-tag at C-terminus& purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 90% as determined by SDS-PAGE. Source Sf9,Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms EPHB2; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5; Developmentally-regulatedEph-related tyrosine kinase; ELK-related tyrosine kinase; EPH tyrosine kinase3; EPH-like kinase 5; hEK5; Renal carcinoma antigen NY-REN-47; Tyrosine-proteinkinase TYRO5; Tyrosine-protein kinase receptor EPH-3.
Amino Acid Sequence VEETLMDSTT ATAELGWMVH PPSGWEEVSG YDENMNTIRT YQVCNVFESSQNNWLRTKFI RRRGAHRIHV EMKFSVRDCS SIPSVPGSCK ETFNLYYYEA DFDSATKTFP NWMENPWVKVDTIAADESFS QVDLGGRVMK INTEVRSFGP VSRSGFYLAF QDYGGCMSLI AVRVFYRKCP RIIQNGAIFQETLSGAESTS LVAARGSCIA NAEEVDVPIK LYCNGDGEWL VPIGRCMCKA GFEAVENGTV CRGCPSGTFKANQGDEACTH CPINSRTTSE GATNCVCRNG YYRADLDPLD MPCTTIPSAP QAVISSVNET SLMLEWTPPRDSGGREDLVY NIICKSCGSG RGACTRCGDN VQYAPRQLGL TEPRIYISDL LAHTQYTFEI QAVNGVTDQSPFSPQFASVN ITTNQAAPSA VSIMHQVSRT VDSITLSWSQ PDQPNGVILD YELQYYEKEL SEYNATAIKSPTNTVTVQGL KAGAIYVFQV RARTVAGYGR YSGKMYFQTM TEAEYQTSIQ EKLPLLEHHH HHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation EPHB2 protein solution (0.5mg/ml) containing PhosphateBuffered Saline (pH 7.4), 1mM DTT and 20% glycerol.

Introduction

EPHReceptor B2 (EPHB2) is a part of the transmembrane Eph receptor tyrosine kinasefamily (RTKs) which binds proteins of the Ephrin family on adjacent cells. Theinteraction leads to contact-dependent bidirectional signaling into neighboringcells. Hippocampal neurons can release vesicles containing full lengthEPHB2, and these are taken up by neighboring glial cells. EPHB2 takes part inthe guidance of commissural axons through the embryonic midline and regulatesdendritic spines development and maturation and stimulates the formation ofexcitatory synapses.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.